Evidence map›Paper›PMID 37612578›Full record

ArticleObesity surgery2023

Roux-en-Y and One-Anastomosis Gastric Bypass Surgery Are Superior to Sleeve Gastrectomy in Lowering Glucose and Cholesterol Levels Independent of Weight Loss: a Propensity-Score Weighting Analysis.

Yi-Cheng Chang, Chih-Neng Hsu, Keong Chong, Po-Jen Yang, Kong-Han Ser, Po-Chu Lee, Shu-Chun Chen, Chin-Feng Hsuan, Yi-Chih Lee, Chih-Cheng Hsu and 9 more

Abstract read
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In one paragraph

Article in Obesity surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 1 pooled it
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
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  3. Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors at 9 institutions in 2 countries.

Yi-Cheng ChangGraduate Institute of Medical Genomics and Proteomics, National Taiwan University, Taipei, 100, Taiwan.
Chih-Neng HsuDivision of Cardiology, Department of Internal Medicine, National Taiwan University Hospital Yunlin Branch, Yunlin, 640, Taiwan.
Keong ChongDepartment of Medicine, Min-Sheng General Hospital, Taoyuan, 330, Taiwan.
Po-Jen YangCenter for Obesity, Lifestyle, and Metabolic Surgery, National Taiwan University Hospital, Taipei, 100, Taiwan.
Kong-Han SerDepartment of Surgery, Ten-Chen General Hospital, Taoyuan, 326, Taiwan.
Po-Chu LeeDepartment of Surgery, National Taiwan University Hospital, Taipei, 100, Taiwan.
Shu-Chun ChenDepartment of Nursing, Ming-Sheng General Hospital, Taoyuan, 330, Taiwan.
Chin-Feng HsuanDepartment of Internal Medicine, Division of Cardiology, E-Da Hospital, Kaohsiung, 824, Taiwan.
Yi-Chih LeeDepartment of International Business, Chien Hsin University of Science and Technology, Taoyuan, 320, Taiwan.
Chih-Cheng HsuInstitute of Population Health Sciences, National Health Research Institutes, Zhunan, 350, Taiwan.
Hsiao-Lin LeeDivision of Endocrinology and Metabolism, Department of Internal Medicine, National Taiwan University Hospital, Taipei, 100, Taiwan.
Karen Chia-Wen LiaoBiological Sciences Division, University of Chicago, Chicago, IL, 60637, USA.
Meng-Lun HsiehDivision of Endocrinology and Metabolism, Department of Internal Medicine, National Taiwan University Hospital, Taipei, 100, Taiwan.
Gwo-Tsann ChuangGraduate Institute of Medical Genomics and Proteomics, National Taiwan University, Taipei, 100, Taiwan.
Wei-Shun YangDivision of Nephrology, Department of Internal Medicine, National Taiwan University Hospital, Hsin-Chu Branch, Hsin-Chu, 302, Taiwan.
Shao-Lun ChuDepartment of Medicine, College of Medicine, National Taiwan University, Taipei, 100, Taiwan.
Wen-Yi LiDivision of Nephrology, Department of Internal Medicine, National Taiwan University Hospital Yunlin Branch, Yunlin, 640, Taiwan.
Lee-Ming ChuangDivision of Endocrinology and Metabolism, Department of Internal Medicine, National Taiwan University Hospital, Taipei, 100, Taiwan. leeming@ntu.edu.tw.
Wei-Jei LeeDepartment of Medicine, Min-Sheng General Hospital, Taoyuan, 330, Taiwan. wjlee_obessurg_tw@yahoo.com.tw.ORCID http://orcid.org/0000-0001-7091-3006
National Taiwan University · TWNational Taiwan University Hospital · TWMin Sheng General Hospital · TWNational Health Research Institutes · TWChien Hsin University of Science and Technology · TWE-Da Hospital · TWTen Chen Hospital · TWUniversity of Chicago · USUniversity of Florida · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe superior effects of gastric bypass surgery in preventing cardiovascular diseases compared with sleeve gastrectomy are well-established. However, whether these effects are independent of weight loss is not known.

methodsIn this retrospective cohort study, we compared the change in cardiometabolic risks of 1073 diabetic patients undergoing Roux-en-Y gastric bypass (RYGB) (n = 265), one-anastomosis gastric bypass (OAGB) (n = 619), and sleeve gastrectomy (SG) (n = 189) with equivalent weight loss from the Min-Shen General Hospital. Propensity score-weighting, multivariate regression, and matching were performed to adjust for baseline differences.

resultsAfter 12 months, OAGB and, to a lesser extent, RYGB exhibited superior effects on glycemic control compared with SG in patients with equivalent weight loss. The effect was significant in patients with mild-to-modest BMI reduction but diminished in patients with severe BMI reduction. RYGB and OAGB had significantly greater effects in lowering total and low-density lipoprotein cholesterol than SG, regardless of weight loss. The results of matching patients with equivalent weight loss yielded similar results. The longer length of bypassed biliopancreatic (BP) limbs was correlated with a greater decrease in glycemic levels, insulin resistance index, lipids, C-reactive protein (CRP) levels, and creatinine levels in patients receiving RYBG. It was correlated with greater decreases in BMI, fasting insulin, insulin resistance index, and C-reactive protein levels in patients receiving OAGB.

conclusionDiabetic patients receiving OAGB and RYGB had lower glucose and cholesterol levels compared with SG independent of weight loss. Our results suggest diabetic patients with cardiovascular risk factors such as hypercholesterolemia to receive bypass surgery.

Indexed as

Diabetes MellitusGastric BypassInsulin ResistanceObesity, MorbidCholesterol, LDLC-Reactive ProteinGastrectomyGlucoseHumansInsulinPropensity ScoreRetrospective StudiesWeight LossCholesterol, LDLC-Reactive ProteinGlucoseInsulinCardiovascular diseasesOne-anastomosis gastric bypassRoux-en-Y gastric bypassSleeve gastrectomy

Identifiers

PMID37612578
OpenAlexW4386085445

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.