ReviewNature reviews. Chemistry2023
From autocatalysis to survival of the fittest in self-reproducing lipid systems.
Review in Nature reviews. Chemistry, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
13 citing papers in PubMed.
- Light and Dark Cycles Control the Structural Evolution of Photoresponsive Supramolecular Systems.Angewandte Chemie (International ed. in English) · 2026Article
- Shedding Light on Synthetic Autocatalysis: From Conventional Closed-Shell Chemistries to Overlooked Open-Shell Occurrences.Chemistry (Weinheim an der Bergstrasse, Germany) · 2026Review
- Enumeration of Autocatalytic Subsystems in Large Chemical Reaction Networks.Journal of chemical theory and computation · 2026Article
- Emergent properties of supramolecular peptide assemblies.Chemical communications (Cambridge, England) · 2026Review
- Article
- Anion-π interaction-induced phase separation as a prebiotic pathway to oxygenation.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- Self-reproduction as an autonomous process of growth and reorganization in fully abiotic, artificial and synthetic cells.Proceedings of the National Academy of Sciences of the United States of America · 2025Article
- The astrochemical evolutionary traits of phospholipid membrane homochirality.Nature reviews. Chemistry · 2024Review
- A Chemical Reaction Network Drives Complex Population Dynamics in Oscillating Self-Reproducing Vesicles.Journal of the American Chemical Society · 2024Article
- Crosstalk between DNA Damage Repair and Metabolic Regulation in Hematopoietic Stem Cells.Cells · 2024Review
- Chiral Induced Spin Selectivity.Chemical reviews · 2024Review
- The GARD Prebiotic Reproduction Model Described in Order and Complexity.Life (Basel, Switzerland) · 2024Article
- A possibility to infer frustrations of supported catalytic clusters from macro-scale observations.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Studying autocatalysis - in which molecules catalyse their own formation - might help to explain the emergence of chemical systems that exhibit traits normally associated with biology. When coupled to other processes, autocatalysis can lead to complex systems-level behaviour in apparently simple mixtures. Lipids are an important class of chemicals that appear simple in isolation, but collectively show complex supramolecular and mesoscale dynamics. Here we discuss autocatalytic lipids as a source of extraordinary behaviour such as primitive chemical evolution, chemotaxis, temporally controllable materials and even as supramolecular catalysts for continuous synthesis. We survey the literature since the first examples of lipid autocatalysis and highlight state-of-the-art synthetic systems that emulate life, displaying behaviour such as metabolism and homeostasis, with special consideration for generating structural complexity and out-of-equilibrium models of life. Autocatalytic lipid systems have enormous potential for building complexity from simple components, and connections between physical effects and molecular reactivity are only just beginning to be discovered.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.