Evidence map›Paper›PMID 37612381›Full record

ReviewNature reviews. Nephrology2023

Diagnosis of cardiovascular disease in patients with chronic kidney disease.

Carmine Zoccali, Patrick B Mark, Pantelis Sarafidis, Rajiv Agarwal, Marcin Adamczak, Rodrigo Bueno de Oliveira, Ziad A Massy, Peter Kotanko, Charles J Ferro, Christoph Wanner and 4 more

Abstract readReview
PubMed Publisher
In one paragraph

Review in Nature reviews. Nephrology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed, 2 pooled it
13.3field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed, 2 syntheses or guidelines pooled it, 67 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  11. Article
  12. Effects of the Brazilian Native Fruit Jaboticaba (Foods (Basel, Switzerland) · 2025
    Article
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  15. ABCDE to identify and prevent chronic kidney disease: a call to action.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 13 institutions in 10 countries.

Carmine ZoccaliRenal Research Institute, New York, NY, USA. carmine.zoccali@icloud.com.ORCID 0000-0002-6616-1996
Patrick B MarkSchool of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.ORCID 0000-0003-3387-2123
Pantelis SarafidisDepartment of Nephrology, Hippokration Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.
Rajiv AgarwalIndiana University School of Medicine, Indianapolis, IN, USA.
Marcin AdamczakDepartment of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia in Katowice, Katowice, Poland.
Rodrigo Bueno de OliveiraDepartment of Internal Medicine (Nephrology), School of Medical Sciences, University of Campinas (Unicamp), Campinas, Brazil.
Ziad A MassyAmbroise Paré University Hospital, APHP, Boulogne Billancourt/Paris, Billancourt, France.
Peter KotankoRenal Research Institute, LLC Icahn School of Medicine at Mount Sinai, New York, NY, USA.ORCID 0000-0003-4373-412X
Charles J FerroDepartment of Renal Medicine, University Hospitals Birmingham, Birmingham, UK.
Christoph WannerDivision of Nephrology, University Hospital of Würzburg, Würzburg, Germany.ORCID 0000-0001-9507-5301
Michel BurnierFaculty of Biology and Medicine, University of Lausanne, Lausanne, Switzerland.ORCID 0000-0003-1283-8487
Raymond VanholderNephrology Section, Department of Internal Medicine and Paediatrics, University Hospital, Ghent, Belgium.ORCID 0000-0003-2633-1636
Francesca MallamaciNephrology and Transplantation Unit, Grande Ospedale Metropolitano Reggio Cal and CNR-IFC, Reggio Calabria, Italy.
Andrzej WiecekDepartment of Nephrology, Transplantation and Internal Medicine, Medical University of Silesia, Katowice, Poland.
Medical University of Silesia · PLAristotle University of Thessaloniki · GRBiogem · ITGhent University Hospital · BEInserm · FRIstituto di Fisiologia Clinica · ITNIHR Surgical Reconstruction and Microbiology Research Centre · GBRenal Research Institute · USRichard L. Roudebush VA Medical Center · USUniversidade Estadual de Campinas (UNICAMP) · BRUniversitätsklinikum Würzburg · DEUniversity of Glasgow · GBUniversity of Lausanne · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Patients with chronic kidney disease (CKD) are at high risk of cardiovascular disease (CVD) and cardiovascular death. Identifying and monitoring cardiovascular complications and hypertension is important for managing patients with CKD or kidney failure and transplant recipients. Biomarkers of myocardial ischaemia, such as troponins and electrocardiography (ECG), have limited utility for diagnosing cardiac ischaemia in patients with advanced CKD. Dobutamine stress echocardiography, myocardial perfusion scintigraphy and dipyridamole stress testing can be used to detect coronary disease in these patients. Left ventricular hypertrophy and left ventricular dysfunction can be detected and monitored using various techniques with differing complexity and cost, including ECG, echocardiography, nuclear magnetic resonance, CT and myocardial scintigraphy. Atrial fibrillation and other major arrhythmias are common in all stages of CKD, and ambulatory heart rhythm monitoring enables precise time profiling of these disorders. Screening for cerebrovascular disease is only indicated in asymptomatic patients with autosomal dominant polycystic kidney disease. Standardized blood pressure is recommended for hypertension diagnosis and treatment monitoring and can be complemented by ambulatory blood pressure monitoring. Judicious use of these diagnostic techniques may assist clinicians in detecting the whole range of cardiovascular alterations in patients with CKD and enable timely treatment of CVD in this high-risk population.

Indexed as

Cardiovascular DiseasesHypertensionRenal Insufficiency, ChronicBlood Pressure Monitoring, AmbulatoryHeartHumans

Identifiers

PMID37612381
OpenAlexW4386090669

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.