ArticleCell metabolism2023
Comprehensive isotopomer analysis of glutamate and aspartate in small tissue samples.
Open access · hybridAbstract read
In one paragraph
Article in Cell metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.
0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.5field-weighted citation impact, top 11% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
14 citing papers in PubMed, 16 citations in OpenAlex.
- Heavy water labeling reveals metabolic flexibility of amino acid and polyamine pathways in mammalian cells.Communications chemistry · 2026Article
- A Stable Isotope Tracing Primer for the Mass Spectrometrist.Annual review of analytical chemistry (Palo Alto, Calif.) · 2026Review
- A targeted metabolomic method to detect epigenetically relevant metabolites.Molecular metabolism · 2026Article
- Analysis of the dynamic metabolic changes during the ripening of wolfberry (Food chemistry: X · 2026Article
- NUDT5 regulates purine metabolism and thiopurine sensitivity by interacting with PPAT.Science (New York, N.Y.) · 2025Article
- Targeted Metabolomic Methods forJournal of proteome research · 2025Article
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- PositionalThe New phytologist · 2025Article
- High Glucose Contribution to the TCA Cycle Is a Feature of Aggressive Non-Small Cell Lung Cancer in Patients.Cancer discovery · 2025Article
- Deciphering the Metabolic Basis and Molecular Circuitry of the Warburg Paradox in Lymphoma.Cancers · 2024Article
- Direct mitochondrial import of lactate supports resilient carbohydrate oxidation.bioRxiv : the preprint server for biology · 2024Article
- Article
- Stable Isotope Tracing Analysis in Cancer Research: Advancements and Challenges in Identifying Dysregulated Cancer Metabolism and Treatment Strategies.Metabolites · 2024Review
- Mitochondrial metabolism in primary and metastatic human kidney cancers.bioRxiv : the preprint server for biology · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
23 authors at 4 institutions in 1 country.
Feng CaiChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: feng.cai@utsouthwestern.edu.
Divya BezwadaChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Ling CaiChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Quantitative Biomedical Research Center, Department of Population and Data Sciences, UT Southwestern Medical Center, Dallas, TX 75390, USA; Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX 75390, USA.
Rohit MaharDepartment of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL 32603, USA.
Zheng WuChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Mario C ChangDepartment of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL 32603, USA.
Panayotis PachnisChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Chendong YangChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Sherwin KelekarChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Wen GuChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Bailey BrooksDepartment of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Bookyung KoChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Hieu S VuChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Thomas P MathewsChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Lauren G ZachariasChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Misty Martin-SandovalChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Duyen DoChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
K Celeste OaxacaChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Eunsook S JinAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Vitaly MargulisDepartment of Urology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA.
Craig R MalloyAdvanced Imaging Research Center, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Veterans Affairs North Texas Healthcare System, Dallas, TX 75216, USA.
Matthew E MerrittDepartment of Biochemistry and Molecular Biology, University of Florida, Gainesville, FL 32603, USA.
Ralph J DeBerardinisChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA; Simmons Comprehensive Cancer Center, UT Southwestern Medical Center, Dallas, TX 75390, USA; Howard Hughes Medical Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA. Electronic address: ralph.deberardinis@utsouthwestern.edu.
Children's Medical Center · USThe University of Texas Southwestern Medical Center · USUniversity of Florida · USSouthwestern Medical Center · US
Funding
UNIVERSITY OF TEXAS--SPORE IN LUNG CANCERP50CA070907 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI GIBBONS, DON LYNN · 1996 to 2024
$57.4MUniversity of Texas Southwestern Medical Center SPORE in Kidney CancerP50CA196516 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI Payal Kapur, Payal Kapur · 2016 to 2026
$24.7MMetabolic Regulators of Tumor Growth and ProgressionR35CA220449 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI RALPH J DEBERARDINIS · 2017 to 2026
$9.4MUT Southwestern NORCP30DK127984 · NIDDK · UT SOUTHWESTERN MEDICAL CENTER · PI JOEL K. ELMQUIST · 2022 to 2026
$7.4MTR&D3-SCHP41GM122698 · NIGMS · FLORIDA STATE UNIVERSITY · PI BREY, WILLIAM W, CROSS, TIMOTHY A · 2017 to 2021
$6.7MNational Resource for Advanced NMR TechnologyRM1GM148766 · NIGMS · FLORIDA STATE UNIVERSITY · PI William W Brey, Joanna R Long · 2023 to 2026
$4.9MImaging Hepatic Energy Metabolism in NAFLD/NASHR01DK132254 · NIDDK · UNIVERSITY OF FLORIDA · PI MERRITT, MATTHEW E · 2022 to 2025
$2.0MWeb Portal CoreU2CDK119889 · NIDDK · UNIVERSITY OF FLORIDA · PI YOST, RICHARD A. · 2018 to 2021
$1.9MNMR console upgrade for structural biology and metabolomicsS10OD028753 · OD · UNIVERSITY OF FLORIDA · PI LONG, JOANNA R · 2020 to 2020
$600kDissecting Fatty Acid Metabolism in Clear Cell Renal Cell Carcinoma (ccRCC)F31CA239330 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI BEZWADA, DIVYA · 2019 to 2021
$103kHoward Hughes Medical InstituteNCI NIH HHS F31 CA239330NCI NIH HHS P50 CA070907NCI NIH HHS P50 CA196516NCI NIH HHS R35 CA220449NIDDK NIH HHS P30 DK127984NIDDK NIH HHS R01 DK132254NIDDK NIH HHS U2C DK119889NIGMS NIH HHS P41 GM122698NIGMS NIH HHS RM1 GM148766NIH HHS S10 OD028753
Abstract
Stable isotopes are powerful tools to assess metabolism.
Indexed as
Aspartic AcidGlutamic AcidCarbon IsotopesCitric Acid CycleHumansMass SpectrometryAspartic AcidCarbon IsotopesGlutamic Acidaspartatecancerglutamateisotopomermass spectrometrynuclear magnetic resonancepyruvate carboxylasestable isotopetricarboxylic acid cycle
Identifiers
What OpenQuestion holds
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LicenceCC BY
Read underepoch 390
Registered trials
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.