Evidence map›Paper›PMID 37611531›Full record

ReviewCurrent opinion in neurobiology2023

Distinguishing subtypes of spinal locomotor neurons to inform circuit function and dysfunction.

Kimberly J Dougherty

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Modeling cerebral palsy in animals.Developmental medicine and child neurology · 2026
    Review
  6. Article
  7. Ontogeny of the spinal cord dorsal horn.Science (New York, N.Y.) · 2026
    Article
  8. Article
  9. Activity of spinal RORβ neurons is related to functional improvements following combination treatment after complete SCI.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  10. Article
  11. Molecular and Cellular Mechanisms of Motor Circuit Development.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Review
  12. Article
  13. Review
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Kimberly J DoughertyMarion Murray Spinal Cord Research Center, Department of Neurobiology and Anatomy, Drexel University College of Medicine, Philadelphia, PA 19129, USA. Electronic address: kjd86@drexel.edu.

Funding

Crucial spinal circuit changes that mediate locomotor benefits and deficits following combined therapies after spinal cord injuryR01NS104194 · NINDS · DREXEL UNIVERSITY · PI Kimberly J Dougherty, SIMON F GISZTER · 2018 to 2026
$4.2M
Mechanisms of locomotor rhythm generation in rodent spinal cordR01NS130799 · NINDS · DREXEL UNIVERSITY · PI Kimberly J Dougherty, Ilya A Rybak · 2022 to 2026
$2.6M
Specific spinal locomotor circuit alterations induced by epidural stimulationR21NS118226 · NINDS · DREXEL UNIVERSITY · PI DOUGHERTY, KIMBERLY J · 2020 to 2020
$416k
NINDS NIH HHS R01 NS104194NINDS NIH HHS R01 NS130799NINDS NIH HHS R21 NS118226
6 · The paper itself

Abstract

Locomotion is a complex motor task executed by spinal neurons. Given the diversity of spinal cord neurons, linking neuronal cell type to function is a challenge. Molecular identification of broad spinal interneuronal classes provided a great advance. Recent studies have used other classifiers, including location, electrophysiological properties, and connectivity, in addition to gene profiling, to narrow the acuity with which groups of neurons can be related to specific functions. However, there are also functional populations without a clear identifier, as exemplified by rhythm generating neurons. Other considerations, including experience or plasticity, add a layer of complexity to the definition of functional subpopulations of spinal neurons, but spinal cord injury may provide insight.

Indexed as

NeuronsSpinal Cord InjuriesHumansInterneuronsLocomotionCentral pattern generatorInterneuronLocomotionRhythm generationSpinal cord injury

Identifiers

PMID37611531
PMCPMC10578609

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.