ArticleIEEE transactions on bio-medical engineering2024
A Physical Model-Based Approach to One-Point Calibration of Pulse Transit Time to Blood Pressure.
Article in IEEE transactions on bio-medical engineering, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Development of a Personalized Multiclass Classification Model to Detect Blood Pressure Variations Associated with Physical or Cognitive Workload.Sensors (Basel, Switzerland) · 2024Article
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4 authors.
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Abstract
objectiveTo develop a novel physical model-based approach to enable 1-point calibration of pulse transit time (PTT) to blood pressure (BP).
methodsThe proposed PTT-BP calibration model is derived by combining the Bramwell-Hill equation and a phenomenological model of the arterial compliance (AC) curve. By imposing a physiologically plausible constraint on the skewness of AC at positive and negative transmural pressures, the number of tunable parameters in the PTT-BP calibration model reduces to 1. Hence, as opposed to most existing PTT-BP calibration models requiring multiple (≥2) PTT-BP measurements to personalize, the PTT-BP calibration model can be personalized to an individual subject using a single PTT-BP measurement pair. Equipped with the physically relevant PTT-AC and AC-BP relationships, the proposed approach may serve as a universal means to calibrate PTT to BP over a wide BP range. The validity and proof-of-concept of the proposed approach were evaluated using PTT and BP measurements collected from 22 healthy young volunteers undergoing large BP changes.
resultsThe proposed approach modestly yet significantly outperformed an empiric linear PTT-BP calibration with a group-average slope and subject-specific intercept in terms of bias (5.5 mmHg vs 6.4 mmHg), precision (8.4 mmHg vs 9.4 mmHg), mean absolute error (7.8 mmHg vs 8.8 mmHg), and root-mean-squared error (8.7 mmHg vs 10.3 mmHg, all in the case of diastolic BP).
conclusionWe demonstrated the preliminary proof-of-concept of an innovative physical model-based approach to one-point PTT-BP calibration. SIGNIFICANCE: The proposed physical model-based approach has the potential to enable more accurate and convenient calibration of PTT to BP.
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