Evidence map›Paper›PMID 37610679›Full record

ArticleHuman cell2023

Identification of a gene set that maintains tumorigenicity of the hepatocellular carcinoma cell line Li-7.

Yusuke Seyama, Kazuhiro Sudo, Suguru Hirose, Yukako Hamano, Takeshi Yamada, Takashi Hiroyama, Ryosuke Sasaki, Masami Yokota Hirai, Ichinosuke Hyodo, Kiichiro Tsuchiya and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Human cell, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.7field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Yusuke SeyamaDivision of Gastroenterology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.ORCID http://orcid.org/0000-0003-1568-3898
Kazuhiro SudoCell Engineering Division, RIKEN BioResource Research Center, Tsukuba, Japan. kazuhiro.sudo@riken.jp.ORCID http://orcid.org/0000-0002-6353-163X
Suguru HiroseDivision of Gastroenterology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Yukako HamanoDepartment of Gastroenterology, Hitachi General Hospital, Hitachi, Japan.
Takeshi YamadaDivision of Gastroenterology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Takashi HiroyamaCell Engineering Division, RIKEN BioResource Research Center, Tsukuba, Japan.
Ryosuke SasakiRIKEN Center for Sustainable Resource Science, Yokohama, Japan.
Masami Yokota HiraiRIKEN Center for Sustainable Resource Science, Yokohama, Japan.
Ichinosuke HyodoDepartment of Gastrointestinal Medical Oncology, National Hospital Organization Shikoku Cancer Center, Matsuyama, Japan.
Kiichiro TsuchiyaDivision of Gastroenterology, Faculty of Medicine, University of Tsukuba, Tsukuba, Japan.
Yukio NakamuraCell Engineering Division, RIKEN BioResource Research Center, Tsukuba, Japan. yukio.nakamura@riken.jp.ORCID http://orcid.org/0000-0001-6834-4123
University of Tsukuba · JPRIKEN BioResource Research Center · JPRIKEN Center for Sustainable Resource Science · JPHitachi General Hospital · JPShikoku Cancer Center · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The identification and development of therapeutic targets in cancer stem cells that lead to tumor development, recurrence, metastasis, and drug resistance is an important goal in cancer research. The hepatocellular carcinoma cell line Li-7 contains functionally different types of cells. Cells with tumor-forming activity are enriched in cancer stem cell-like CD13

Indexed as

CarcinogenesisCarcinoma, HepatocellularLiver NeoplasmsNeoplastic Stem CellsAnimalsCell Line, TumorCulture MediaHumansCulture MediaCancer stem cellCD13 expressionHepatocellular carcinomaRNA sequencingTumorigenicity

Identifiers

PMID37610679
PMCPMC10587214
OpenAlexW4386083772

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.