Evidence map›Paper›PMID 37610650›Full record

ArticleRheumatology international2023

Higher frequency but similar recurrence rate of uveitis episodes in axial spondylarthritis compared to psoriatic arthritis. A multicentre retrospective study.

Nikolaos Kougkas, Konstantina Magiouf, Chrysoula G Gialouri, Gerasimos Evangelatos, Maria Pappa, Aikaterini Dimouli, Alexios Iliopoulos, Anastasios Karmanakos, Theodoros Dimitroulas, Maria G Tektonidou and 2 more

Open access · hybridAbstract readMulticenter Study
In one paragraph

Article in Rheumatology international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Observational
  3. Article
  4. Interpretable Machine Learning for Predicting Anterior Uveitis in Axial Spondyloarthritis.Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases · 2025
    Article
  5. Uveitis in Psoriatic Arthritis: A Comprehensive Review.European journal of rheumatology · 2025
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Nikolaos Kougkas *Department of Rheumatology, Ippokration Hospital, Thessaloniki, Greece.ORCID http://orcid.org/0000-0001-5275-8639
Konstantina Magiouf *Joint Academic Rheumatology Program, First Department of Propedeutic and Internal Medicine, National and Kapodistrian University of Athens, Athens, Greece.ORCID http://orcid.org/0009-0007-1662-4132
Chrysoula G GialouriJoint Academic Rheumatology Program, First Department of Propedeutic and Internal Medicine, National and Kapodistrian University of Athens, Athens, Greece.ORCID http://orcid.org/0000-0002-1310-7902
Gerasimos EvangelatosDepartment of Rheumatology, 417 Army Share Found Hospital (NIMTS), Athens, Greece.ORCID http://orcid.org/0000-0003-3822-3093
Maria PappaJoint Academic Rheumatology Program, First Department of Propedeutic and Internal Medicine, National and Kapodistrian University of Athens, Athens, Greece.ORCID http://orcid.org/0000-0003-1296-0693
Aikaterini DimouliDepartment of Rheumatology, "Evangelismos" General Hospital, Athens, Greece.ORCID http://orcid.org/0009-0001-0884-1870
Alexios IliopoulosJoint Academic Rheumatology Program, Clinical Immunology, Rheumatology unit, Second Department of Medicine and Laboratory, National and Kapodistrian University of Athens, Athens, Greece.ORCID http://orcid.org/0000-0001-7107-1664
Anastasios KarmanakosDepartment of Rheumatology, "Evangelismos" General Hospital, Athens, Greece.ORCID http://orcid.org/0000-0002-3006-9362
Theodoros DimitroulasDepartment of Rheumatology, Ippokration Hospital, Thessaloniki, Greece.ORCID http://orcid.org/0000-0002-0364-1642
Maria G TektonidouJoint Academic Rheumatology Program, First Department of Propedeutic and Internal Medicine, National and Kapodistrian University of Athens, Athens, Greece.ORCID http://orcid.org/0000-0003-2238-0975
Petros P SfikakisJoint Academic Rheumatology Program, First Department of Propedeutic and Internal Medicine, National and Kapodistrian University of Athens, Athens, Greece.ORCID http://orcid.org/0000-0001-5484-2930
George E FragoulisJoint Academic Rheumatology Program, First Department of Propedeutic and Internal Medicine, National and Kapodistrian University of Athens, Athens, Greece. geofragoul@yahoo.gr.ORCID http://orcid.org/0000-0003-4932-7023
National and Kapodistrian University of Athens · GREvangelismos Hospital · GRIppokrateio General Hospital of Thessaloniki · GRNIMTS Hospital · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND/

objectiveData on risk factors predicting uveitis development in spondyloarthritis (SpA) is scarce. Our aim was to examine associations between demographic, clinical and/or laboratory characteristics of SpA with the occurrence and the course of uveitis, including ocular damage and recurrence rate.

methodsCharacteristics (at disease diagnosis and ever-present) from axSpA and Psoriatic arthritis (PsA) patients followed in 3 tertiary rheumatology-clinics were retrospectively recorded. Comparisons were made between patients with and without uveitis, as well as between those with uveitis-rate [episodes/year] above the median uveitis-rate in the whole cohort ("recurrent"-uveitis) and the remaining uveitis patients ("non-recurrent uveitis"). In multivariable models, age, gender and variables significantly different in univariate analyses were included.

results264 axSpA and 369 PsA patients were enrolled. In axSpA, uveitis occurred in 11.7% and was associated with HLA-B27 (OR = 4.15, 95%CI 1.16-14.80, p = 0.028) and ever-present peripheral arthritis (OR = 3.05 (1.10-8.41, p = 0.031). In contrast, uveitis in PsA occurred only in 2.7% of patients and was associated with SpA family-history (OR = 6.35 (1.29-31.27), p = 0.023) axial disease at diagnosis (OR = 5.61 [1.01-28.69], p = 0.038) and disease duration (OR = 1.12 [1.04-1.21], p = 0.004). Median uveitis recurrence rate was comparable between axSpA and PsA (0.205 and 0.285 episodes/year, respectively). No associations were found between recurrent uveitis and demographic/clinical/laboratory characteristics. Ocular damage (e.g. synechiae) was seen in 16.1% of axSpA and 30% of PsA patients, all of them with recurrent uveitis.

conclusionUveitis occurred more commonly in axSpA than in PsA patients, while uveitis recurrence rate was similar. Permanent ocular damage may occur more often in PsA than axSpA.

Indexed as

Arthritis, PsoriaticAxial SpondyloarthritisSpondylarthritisUveitisHumansRetrospective StudiesPsoriatic arthritisSpondyloarthritisUveitis

Identifiers

PMID37610650
PMCPMC10495278
OpenAlexW4386084269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.