Evidence map›Paper›PMID 37610496›Full record

ReviewClinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico2023

An overview on the relationship between residential radon and lung cancer: what we know and future research.

Alberto Ruano-Ravina, Lucia Martin-Gisbert, Karl Kelsey, Mónica Pérez-Ríos, Cristina Candal-Pedreira, Julia Rey-Brandariz, Leonor Varela-Lema

Open access · hybridAbstract readReview
In one paragraph

Review in Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.

  1. Association between second-hand smoke exposure and lung cancer risk in never-smokers: a systematic review and meta-analysis.European respiratory review : an official journal of the European Respiratory Society · 2024
    Pooled it
  2. Review
  3. Article
  4. Article
  5. A world map of air pollution and EGFR-mutant prevalence.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Trends in lung cancer incidence in Spain (1990-2019): insights from Global Burden of Diseases data.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Alberto Ruano-RavinaDepartment of Preventive Medicine and Public Health, Facultade de Medicina, University of Santiago de Compostela, Rua San Francisco S/N, 15782, Santiago de Compostela, Spain.ORCID http://orcid.org/0000-0001-9927-7453
Lucia Martin-GisbertDepartment of Preventive Medicine and Public Health, Facultade de Medicina, University of Santiago de Compostela, Rua San Francisco S/N, 15782, Santiago de Compostela, Spain. lucia.martin.de@rai.usc.es.ORCID http://orcid.org/0000-0002-4641-2129
Karl KelseyDepartment of Epidemiology, Brown School of Public Health, Brown University, Providence, RI, USA.ORCID http://orcid.org/0000-0002-2302-1600
Mónica Pérez-RíosDepartment of Preventive Medicine and Public Health, Facultade de Medicina, University of Santiago de Compostela, Rua San Francisco S/N, 15782, Santiago de Compostela, Spain.ORCID http://orcid.org/0000-0003-4456-6631
Cristina Candal-PedreiraDepartment of Preventive Medicine and Public Health, Facultade de Medicina, University of Santiago de Compostela, Rua San Francisco S/N, 15782, Santiago de Compostela, Spain.ORCID http://orcid.org/0000-0002-1703-3592
Julia Rey-BrandarizDepartment of Preventive Medicine and Public Health, Facultade de Medicina, University of Santiago de Compostela, Rua San Francisco S/N, 15782, Santiago de Compostela, Spain.ORCID http://orcid.org/0000-0002-2960-8437
Leonor Varela-LemaDepartment of Preventive Medicine and Public Health, Facultade de Medicina, University of Santiago de Compostela, Rua San Francisco S/N, 15782, Santiago de Compostela, Spain.ORCID http://orcid.org/0000-0001-8365-7961
Universidade de Santiago de Compostela · ESBrown University · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We aim to provide an overview of the research available on indoor radon and lung cancer, with a special focus on Spanish investigations. Early studies on underground miners established the link between radon and lung cancer, which was later confirmed for the general population by residential case-control studies. Spain contributed with extensive evidence, including 5 multicentric, hospital-based, case-control studies in the last 30 years, exploring diverse aspects, such as radon's effect on never-smokers, molecular pathways linking radon exposure to lung cancer risk, survival rates, mortality burden, and occupational exposure. There is a well-established causal association between radon with lung cancer. Despite pioneering research performed in our country by the Galician Radon Laboratory, particularly on driver genes, the evidence on the potential molecular pathways which makes radon a carcinogen is sparse. Also, relevant questions on the potential association of radon exposure with the induction of other diseases are still pending.

Indexed as

Air Pollution, IndoorLung NeoplasmsNeoplasms, Radiation-InducedRadonHumansRiskRadonExposureLung cancerMolecular pathwaysRadon

Identifiers

PMID37610496
PMCPMC10603006
OpenAlexW4386084584

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.