Evidence map›Paper›PMID 37610390›Full record

Observational studyThe Journal of adolescent health : official publication of the Society for Adolescent Medicine2023

Mental Health and Gender Affirmation of Black and Latine Transgender/Nonbinary Youth Compared to White Peers Prior to Hormone Initiation.

Stanley R Vance, Diane Chen, Robert Garofalo, David V Glidden, Diane Ehrensaft, Marco Hidalgo, Amy Tishelman, Stephen M Rosenthal, Yee-Ming Chan, Johanna Olson-Kennedy and 1 more

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in The Journal of adolescent health : official publication of the Society for Adolescent Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Social transition in young trans people accessing gender-affirming care.International journal of transgender health · 2026
    Article
  4. Article
  5. Article
  6. Community-Derived Recommendations for Improving Gender Affirmation of Black and Latine Transgender/Nonbinary Youth.Annals of behavioral medicine : a publication of the Society of Behavioral Medicine · 2024
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Stanley R VanceChild and Adolescent Gender Center, Division of Adolescent and Young Adult Medicine, Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, California. Electronic address: stanley.vance@ucsf.edu.
Diane ChenGender and Sex Development Program, Potoscnak Family Division of Adolescent and Young Adult Medicine, and Pritzker Department of Psychiatry and Behavioral Health, Ann and Robert H. Lurie's Children's Hospital, Chicago, Illinois; Department of Psychiatry and Behavioral Sciences, and Pediatrics, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
Robert GarofaloGender and Sex Development Program, Potoscnak Family Division of Adolescent and Young Adult Medicine, Department of Pediatrics, Ann and Robert H. Lurie's Children's Hospital, Northwestern University Feinberg School of Medicine, Chicago, Illinois.
David V GliddenDepartment of Epidemiology and Biostatistics, University of California, San Francisco, San Francisco, California.
Diane EhrensaftChild and Adolescent Gender Center, Division of Pediatric Endocrinology, Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, California.
Marco HidalgoGender Health Program, Medicine-Pediatrics Division, General Internal Medicine and Health Services Research, Department of Medicine, David Geffen School of Medicine at University of California, Los Angeles, Los Angeles, California.
Amy TishelmanDepartment of Psychology and Neuroscience, Boston College, Chestnut Hill, Massachusetts.
Stephen M RosenthalChild and Adolescent Gender Center, Division of Pediatric Endocrinology, Department of Pediatrics, Benioff Children's Hospital, University of California, San Francisco, San Francisco, California.
Yee-Ming ChanDivision of Endocrinology, Department of Pediatrics, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts.
Johanna Olson-KennedyCenter for Transyouth Health and Development, Division of Adolescent and Young Adult Medicine, Department of Pediatrics, Children's Hospital Los Angeles, Keck School of Medicine, University of Southern California, Los Angeles, California.
Jae SeveliusDepartment of Medicine, Center for AIDS Prevention Studies, University of California, San Francisco, California.

Funding

The Impact of Early Medical Treatment in Transgender YouthR01HD082554 · NICHD · CHILDREN'S HOSPITAL OF LOS ANGELES · PI CHAN, YEE-MING, GAROFALO, ROBERT · 2015 to 2024
$9.7M
Mentoring clinical investigators in patient-oriented research on substance use and HIVK24DA051328 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI SEVELIUS, JAE M. · 2020 to 2024
$771k
Examining Contributors to Disparities in Gender Affirmation and Mental Health among Black and Latinx Transgender YouthK23MD015044 · NIMHD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI VANCE, STANLEY RAY · 2022 to 2024
$411k
NICHD NIH HHS R01 HD082554NIDA NIH HHS K24 DA051328NIMHD NIH HHS K23 MD015044
6 · The paper itself

Abstract

purposeTo compare baseline mental health symptoms and gender affirmation between Black/Latine versus White transgender/nonbinary youth (BLTY vs. WTY) and examine relationships between gender affirmation and mental health symptoms, and whether associations differed by race/ethnicity subgroup.

methodsBaseline data were analyzed from the gender-affirming hormone cohort of the Trans Youth Care United States Study-a 4-clinic site, observational study. Mental health symptoms assessed included depression, suicidality, and anxiety. Gender affirmation measures included the parental acceptance subscale from the perceived Parental Attitudes of Gender Expansiveness Scale-Youth Report; non-affirmation, internalized transphobia, and community connectedness subscales from the Gender Minority Stress and Resilience Measure-Adolescent; and self-reported living full time in affirmed gender. Fisher exact tests and independent sample t tests compared mental health symptoms and gender affirmation between subgroups. Logistic regression analyses evaluated associations between gender affirmation and mental health symptoms. Interaction analyses assessed differences in associations between subgroups.

resultsThe sample (mean age 16 years, range 12-20 years) included 92 BLTY (35%) and 170 WTY (65%). Subgroups had comparable prevalence of depression and anxiety symptoms. WTY had higher prevalence of lifetime suicidality (73% vs. 59%; p = .02). There were no differences in gender affirmation. Among the whole sample, higher parental acceptance decreased odds of depression symptoms. Not living in affirmed gender increased odds of depression symptoms. Higher non-affirmation and internalized transphobia increased odds of depression and anxiety symptoms and suicidality. Associations did not vary by subgroup. DISCUSSION: BLTY and WTY had comparable mental health symptoms. For both subgroups, gender affirmation decreased odds of those symptoms.

Indexed as

Mental DisordersTransgender PersonsAdolescentAdultChildFemaleGender IdentityHumansMaleMental HealthUnited StatesWhiteYoung AdultGender affirmationMental healthTransgender persons

Identifiers

PMID37610390
PMCPMC10723039

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.