Evidence map›Paper›PMID 37610232›Full record

ArticleMicrobiology spectrum2023

Genome-wide translational response of

Saket Choudhary, Vasanthakrishna Mundodi, Andrew D Smith, David Kadosh

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.2field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
  3. 2-Nonanol produced byFrontiers in microbiology · 2025
    Article
  4. Article
  5. The putative error prone polymerasenpj antimicrobials and resistance · 2024
    Article
  6. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Saket Choudhary *Quantitative and Computational Biology, University of Southern California , Los Angeles, California, USA.
Vasanthakrishna Mundodi *Department of Microbiology, Immunology, and Molecular Genetics, University of Texas Health Science Center at San Antonio , San Antonio, Texas, USA.
Andrew D SmithQuantitative and Computational Biology, University of Southern California , Los Angeles, California, USA.
David KadoshDepartment of Microbiology, Immunology, and Molecular Genetics, University of Texas Health Science Center at San Antonio , San Antonio, Texas, USA.ORCID 0000-0001-7237-8481
The University of Texas Health Science Center at San Antonio · USUniversity of Southern California · US

Funding

TISSUE CULTURE---COREP30CA054174 · NCI · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI Robin Jean Leach · 1991 to 2026
$59.1M
Translational Control of Morphology and Virulence in Candida albicansR01AI127692 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI KADOSH, DAVID · 2018 to 2022
$1.9M
Illumina NovaSeq 6000 Sequencing SystemS10OD030311 · OD · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI LAI, ZHAO · 2021 to 2021
$600k
Regulation of Protein Synthesis During the C. albicans-Macrophage InteractionR21AI142560 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI KADOSH, DAVID · 2019 to 2020
$435k
Translational Control of Antifungal Resistance in Candida albicansR21AI130668 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI KADOSH, DAVID · 2017 to 2018
$431k
Translational Regulation of Candida glabrata Azole ResistanceR21AI172207 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI KADOSH, DAVID · 2023 to 2024
$426k
Regulation of Multidrug Resistance in the Emerging Human Fungal Pathogen Candida aurisR21AI164719 · NIAID · UNIVERSITY OF TEXAS HLTH SCIENCE CENTER · PI KADOSH, DAVID · 2021 to 2022
$426k
HHS | National Institutes of Health (NIH) R21AI130668, R01AI127692, R21AI172207, R21AI164719, R21AI142560NCI NIH HHS P30 CA054174NIAID NIH HHS R01 AI127692NIAID NIH HHS R21 AI130668NIAID NIH HHS R21 AI142560NIAID NIH HHS R21 AI164719NIAID NIH HHS R21 AI172207NIH HHS S10 OD030311
6 · The paper itself

Abstract

importanceAzoles are one of the most commonly used drug classes to treat human fungal pathogens. While point mutations, chromosomal rearrangements, and transcriptional mechanisms that drive azole resistance have been well-characterized, we know very little about the role of translational mechanisms. In this study, we determined the global translational profile of genes that are expressed in the major human fungal pathogen

Indexed as

Candida albicansfluconazoleribosome profilingtranscriptional profilingtranslational control

Identifiers

PMID37610232
PMCPMC10580883
OpenAlexW4386084914

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.