Evidence map›Paper›PMID 37610217›Full record

ArticleMicrobiology spectrum2023

Epidemiology and risk factors for recurrence in biliary source bloodstream infection episodes in oncological patients.

Ignacio Grafia, Mariana Chumbita, Elia Seguí, Celia Cardozo, Juan Carlos Laguna, Marta García de Herreros, Nicole Garcia-Pouton, Ana Villaescusa, Cristina Pitart, Verónica Rico-Caballero and 12 more

Open access · goldAbstract read
In one paragraph

Article in Microbiology spectrum, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Predictive value of platelet count-related ratios for severity in biliary Escherichia coli and Klebsiella pneumonia bloodstream infections.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2025
    Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

22 authors at 2 institutions in 1 country.

Ignacio GrafiaMedical Oncology Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Mariana ChumbitaInfectious Diseases Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Elia SeguíMedical Oncology Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Celia CardozoInfectious Diseases Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Juan Carlos LagunaMedical Oncology Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Marta García de HerrerosMedical Oncology Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Nicole Garcia-PoutonInfectious Diseases Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Ana VillaescusaMedical Oncology Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Cristina PitartMicrobiology Department, Centre Diagnòstic Biomèdic, Hospital Clínic , Barcelona, Spain.
Verónica Rico-CaballeroInfectious Diseases Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Javier Marco-HernándezInternal Medicine Department, Supportive and Palliative Care in Cancer Unit, Hospital Clínic , Barcelona, Spain.
Carles ZamoraMedical Oncology Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Margarita ViladotMedical Oncology Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Joan PadrosaMedical Oncology Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Albert TucaMedical Oncology Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Eric Mayor-VázquezMedical Intensive Care Unit, Internal Medicine Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Francesc MarcoMicrobiology Department, Centre Diagnòstic Biomèdic, Hospital Clínic , Barcelona, Spain.
Jose A MartínezInfectious Diseases Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Josep MensaInfectious Diseases Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Carolina Garcia-VidalInfectious Diseases Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Alex SorianoInfectious Diseases Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.
Pedro Puerta-AlcaldeInfectious Diseases Department, Hospital Clínic-IDIBAPS , Barcelona, Spain.ORCID 0000-0003-2490-0217
Hospital Clínic de Barcelona · ESCentro de Investigación Biomédica en Red · ES

Funding

MEC | Instituto de Salud Carlos III (ISCIII) ICI21/00103MEC | Instituto de Salud Carlos III (ISCIII) JR20/00012MEC | Instituto de Salud Carlos III (ISCIII) PI21/00498MEC | Instituto de Salud Carlos III (ISCIII) PI21/01640
6 · The paper itself

Abstract

importanceThis study shows that biliary source bloodstream infections (BSIs) in oncological patients are mainly caused by Gram-negative bacilli (GNB), with high and increasing rates of multidrug resistance. Importantly, recurrent biliary source BSI episodes were very frequent and associated with delays in chemotherapy, high rates of inappropriate empirical antibiotic therapy, and high 30-d mortality (19.5%). Using the variable independently associated with recurrent BSI episodes, a score was generated that predicted recurrent biliary source BSI with high accuracy. This score could be used to establish prophylactic strategies and lower the risk of relapsing episodes and the associated morbidity and mortality.

Indexed as

biliary source bloodstream infectioncholangitisempirical treatmentmortalityrecurrence

Identifiers

PMID37610217
PMCPMC10580831
OpenAlexW4386084088

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.