ArticleAnnals of the Royal College of Surgeons of England2024
Appendicolith appendicitis: should we be operating sooner? A retrospective cohort study.
Article in Annals of the Royal College of Surgeons of England, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- The Cost-Effectiveness of Conservatively Managed Acute Appendicitis Versus Appendicectomy: A Systematic Review.Surgical laparoscopy, endoscopy & percutaneous techniques · 2026Pooled it
- One year follow up outcomes of endoscopic retrograde appendicitis treatment for symptomatic appendicoliths.iScience · 2026Article
- A novel CT-based scoring system for appendicoliths and its prognostic value in acute appendicitis: a retrospective cohort study.Emergency radiology · 2026Article
- Appendicolith detection in dual-energy CT of adult acute appendicitis: comparing portovenous phase and virtual noncontrast with true noncontrast images.Abdominal radiology (New York) · 2026Article
- Appendicolith and inflammatory burden in pediatric acute appendicitis: an independent association.Pediatric surgery international · 2026Article
- Case Report: Diagnostic challenges in pediatric appendicitis: a case of perforated appendicitis with secondary hepatic abscess.Frontiers in pediatrics · 2026Article
- Hepatic Abscess Secondary to a Retained Appendicolith Following Perforated Appendicitis: A Case Report.Cureus · 2025Article
- Diagnostic value of the MZXBTCH scoring system for acute complex appendicitis.Scientific reports · 2025Article
- Impact of an appendicolith and its characteristics on the severity of acute appendicitis.BJS open · 2024Article
- Hidden Appendicoliths and Their Impact on the Severity and Treatment of Acute Appendicitis.Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
6 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
introductionEvidence suggests that delaying an appendicectomy for up to 24 hours does not increase the risk of complicated appendicitis. Appendicoliths are a risk factor for perforation. No study has explored the temporal relationship between appendicolith presence and time to perforation. In this retrospective cohort study, we hypothesise that the presence of an appendicolith confirmed on preoperative computerised tomography scan (pCT) leads to a shorter time to complicated appendicitis.
methodsWe undertook a retrospective single-centre study of patients admitted between 2018 and 2020. Inclusion criteria included: age ≥18 years, appendicitis confirmed on histopathology following an operation and a pCT scan. Complicated appendicitis was defined intraoperatively as an appendicular abscess, gangrenous or perforated appendix.
resultsSome 310 patients were included in the study. Forty-five per cent presented with complicated appendicitis (
conclusionsPatients with an appendicolith appendicitis should be considered for an early appendicectomy. Future large-scale multicentre prospective studies are required to explore this further, perhaps informing future guidelines.
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