ArticleIndian journal of thoracic and cardiovascular surgery2023
The oral microbiota in patients undergoing coronary artery bypass graft surgery.
Article in Indian journal of thoracic and cardiovascular surgery, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
The oral cavity houses a diverse community of microorganisms which play an important role in maintaining the health of the individual. The coexistence of periodontal infections with coronary artery disease (CAD) has been shown in many studies. We investigated the presence and abundance of periodontitis-causing bacteria in patients with CAD. The oral microbiome of five patients admitted for coronary artery bypass graft (CABG) surgery was analysed by metagenomic sequencing of 16 s ribosomal ribonucleic acid (rRNA) gene amplicons. Two samples of oral mouthwash were collected 48-72 h apart when the patients were in the intensive care unit. Abundance and diversity of oral bacterial flora were analysed. The most abundant phyla were Firmicutes and Bacteroidetes. Less than 5% of the taxa in this group of patients belonged to the phylum Proteobacteria. Though there were variations in the abundance of the bacterial species in the immediate postoperative period, there was no major change in the overall diversity. High counts of periodontal pathogens such as
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