Evidence map›Paper›PMID 37609277›Full record

ArticlebioRxiv : the preprint server for biology2023

Cell-type-specific plasticity shapes neocortical dynamics for motor learning.

Shouvik Majumder, Koichi Hirokawa, Zidan Yang, Ronald Paletzki, Charles R Gerfen, Lorenzo Fontolan, Sandro Romani, Anant Jain, Ryohei Yasuda, Hidehiko K Inagaki

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Shouvik MajumderMax Planck Florida Institute for Neuroscience, Jupiter, FL 33458, USA.
Koichi HirokawaMax Planck Florida Institute for Neuroscience, Jupiter, FL 33458, USA.
Zidan YangMax Planck Florida Institute for Neuroscience, Jupiter, FL 33458, USA.
Ronald PaletzkiNational Institute of Mental Health, Bethesda, MD 20814, USA.
Charles R GerfenNational Institute of Mental Health, Bethesda, MD 20814, USA.
Lorenzo FontolanTuring Centre for Living Systems, Aix- Marseille University, INSERM, INMED U1249, Marseille, France.
Sandro RomaniJanelia Research Campus, HHMI, Ashburn VA 20147, USA.
Anant JainMax Planck Florida Institute for Neuroscience, Jupiter, FL 33458, USA.
Ryohei YasudaMax Planck Florida Institute for Neuroscience, Jupiter, FL 33458, USA.
Hidehiko K InagakiMax Planck Florida Institute for Neuroscience, Jupiter, FL 33458, USA.
Max Planck Florida Institute for Neuroscience · USNational Institute of Mental Health · USInserm · FRJanelia Research Campus · US

Funding

Functional Organization Of The Cerebral Cortex and Basal GangliaZIAMH002497 · NIMH · NATIONAL INSTITUTE OF MENTAL HEALTH · PI GERFEN, CHARLES R · 2009 to 2025
$18.3M
A Novel Approach to Crack Neuronal Mechanisms that Shape Computations in the BrainDP2NS132108 · NINDS · MAX PLANCK FLORIDA CORPORATION · PI INAGAKI, HIDEHIKO · 2022 to 2025
$2.9M
Intramural NIH HHS ZIA MH002497NINDS NIH HHS DP2 NS132108
6 · The paper itself

Abstract

Neocortical spiking dynamics control aspects of behavior, yet how these dynamics emerge during motor learning remains elusive. Activity-dependent synaptic plasticity is likely a key mechanism, as it reconfigures network architectures that govern neural dynamics. Here, we examined how the mouse premotor cortex acquires its well-characterized neural dynamics that control movement timing, specifically lick timing. To probe the role of synaptic plasticity, we have genetically manipulated proteins essential for major forms of synaptic plasticity, Ca

Identifiers

PMID37609277
PMCPMC10441538
OpenAlexW4385765490

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.