Evidence map›Paper›PMID 37609269›Full record

ArticlemedRxiv : the preprint server for health sciences2023

Increasing activity after stroke: a randomized controlled trial of highintensity walking and step activity intervention.

Elizabeth D Thompson, Ryan T Pohlig, Kiersten M McCartney, T George Hornby, Scott E Kasner, Jonathan Raser-Schramm, Allison E Miller, Christopher E Henderson, Henry Wright, Tamara Wright and 1 more

Registry-linked trialOpen access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06970210 (United4Stroke), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06970210 naenrolling by invitationnot on this mapstarted 2025, after this paper: background citation

United4Stroke (U4S) - El Paso Network: Community Health Program With Group-Based Education

TypeinterventionalSponsorUniversity of Texas, El PasoRan2025 to 2028Enrolled46ConditionsStrokeArmsGroup-Based Education, Individualized Coaching
3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 5 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 1 country.

Elizabeth D ThompsonUniversity of Delaware, Department of Physical Therapy, Newark, DE, USA.
Ryan T PohligUniversity of Delaware, Biostatistics Core, Newark, DE, USA.
Kiersten M McCartneyUniversity of Delaware, Biomechanics and Movement Science (BIOMS) program, Newark, DE, USA.
T George HornbyIndiana University, Department of Physical Medicine and Rehabilitation, Indianapolis, IN, USA.
Scott E KasnerUniversity of Pennsylvania, Perelman School of Medicine, Philadelphia, PA, USA.
Jonathan Raser-SchrammChristiana Care Health System, Newark, DE, USA.
Allison E MillerWashington University School of Medicine, Program in Physical Therapy, St. Louis, MO, USA.
Christopher E HendersonIndiana University, Department of Physical Medicine and Rehabilitation, Indianapolis, IN, USA.
Henry WrightUniversity of Delaware, Department of Physical Therapy, Newark, DE, USA.
Tamara WrightUniversity of Delaware, Department of Physical Therapy, Newark, DE, USA.
Darcy S ReismanUniversity of Delaware, Department of Physical Therapy, Newark, DE, USA.
University of Delaware · USRehabilitation Hospital of Indiana · USChristiana Care Health System · USUniversity of Pennsylvania · USWashington University in St. Louis · US

Funding

Promoting Recovery Optimization with WALKing Exercise after Stroke (PROWALKS)R01HD086362 · NICHD · UNIVERSITY OF DELAWARE · PI REISMAN, DARCY S. · 2016 to 2020
$4.0M
NICHD NIH HHS R01 HD086362
6 · The paper itself

Abstract

Background: Physical inactivity in people with chronic stroke profoundly affects daily function and increases recurrent stroke risk and mortality, making physical activity improvements an important target of intervention. We compared the effects of a highintensity walking intervention (FAST), a step activity monitoring behavioral intervention (SAM), or a combined intervention (FAST+SAM) on physical activity (i.e., steps per day). We hypothesized the combined intervention would yield the greatest increase in steps per day. Methods: This assessor-blinded multi-site randomized controlled trial was conducted at four university/hospital-based laboratories. Participants were 21-85 years old, walking without physical assistance following a single, unilateral non-cerebellar stroke of ≥6 months duration, and randomly assigned to FAST, SAM, or FAST+SAM for 12 weeks (2-3 sessions/week). FAST training consisted of walking-related activities for 40 minutes/session at 70-80% heart rate reserve, while SAM received daily feedback and goal-setting of walking activity (steps per day). Assessors and study statistician were masked to group assignment.The Findings: Participants were enrolled from July 18, 2016-November 16, 2021. Of 250 randomized participants (mean[SE] age 63[0.80], 116F/134M), 89 were assigned to FAST, 81 to SAM, and 80 to FAST+SAM. Steps per day significantly increased in both the SAM (mean[SE] 1542[267], 95%CI:1014-2069, Interpretation: Only individuals with chronic stroke who completed a step activity monitoring behavioral intervention with skilled coaching and goal progression demonstrated improvements in physical activity (steps per day).

Indexed as

high-intensity gaitstep activity monitoringstroketreadmillwalking

Identifiers

PMID37609269
PMCPMC10441496
OpenAlexW4382055473

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.