Evidence map›Paper›PMID 37609253›Full record

ArticlebioRxiv : the preprint server for biology2023

Glial-derived mitochondrial signals impact neuronal proteostasis and aging.

Raz Bar-Ziv, Naibedya Dutta, Adam Hruby, Edward Sukarto, Maxim Averbukh, Athena Alcala, Hope R Henderson, Jenni Durieux, Sarah U Tronnes, Qazi Ahmad and 7 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

17 authors.

Raz Bar-ZivDepartment of Molecular & Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley CA 94720, USA.
Naibedya DuttaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.
Adam HrubyLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.
Edward SukartoDepartment of Molecular & Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley CA 94720, USA.
Maxim AverbukhLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.
Athena AlcalaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.
Hope R HendersonDepartment of Molecular & Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley CA 94720, USA.
Jenni DurieuxDepartment of Molecular & Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley CA 94720, USA.
Sarah U TronnesDepartment of Molecular & Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley CA 94720, USA.
Qazi AhmadDepartment of Molecular & Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley CA 94720, USA.
Theodore BolasDepartment of Molecular & Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley CA 94720, USA.
Joel PerezDepartment of Molecular & Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley CA 94720, USA.
Julian G DishartDepartment of Molecular & Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley CA 94720, USA.
Matthew VegaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.
Gilberto GarciaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.
Ryo Higuchi-SanabriaLeonard Davis School of Gerontology, University of Southern California, Los Angeles, CA 90089, USA.
Andrew DillinDepartment of Molecular & Cellular Biology, Howard Hughes Medical Institute, The University of California, Berkeley, Berkeley CA 94720, USA.

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Aric L Daul, Ann E. Rougvie · 2012 to 2026
$7.5M
Neuroendocrine Coordination of Mitochondrial Stress Signaling and ProteostasisR01ES021667 · NIEHS · UNIVERSITY OF CALIFORNIA BERKELEY · PI DILLIN, ANDREW G · 2012 to 2023
$4.6M
More than just a load control: cytoskeletal form and function during agingR00AG065200 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI HIGUCHI-SANABRIA, RYO · 2021 to 2023
$747k
NIA NIH HHS R00 AG065200NIEHS NIH HHS R01 ES021667NIH HHS P40 OD010440
6 · The paper itself

Abstract

The nervous system plays a critical role in maintaining whole-organism homeostasis; neurons experiencing mitochondrial stress can coordinate the induction of protective cellular pathways, such as the mitochondrial unfolded protein response (UPR

Indexed as

agingC. elegansgliamitochondrianeurodegenerationprotein homeostasis

Identifiers

PMID37609253
PMCPMC10441375

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.