Evidence map›Paper›PMID 37609176›Full record

ArticlebioRxiv : the preprint server for biology2023

Analytical code sharing practices in biomedical research.

Nitesh Kumar Sharma, Ram Ayyala, Dhrithi Deshpande, Yesha M Patel, Viorel Munteanu, Dumitru Ciorba, Andrada Fiscutean, Mohammad Vahed, Aditya Sarkar, Ruiwei Guo and 5 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

15 authors.

Nitesh Kumar SharmaTitus Family Department of Clinical Pharmacy, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, 1540 Alcazar Street, Los Angeles, CA 90033, USA.ORCID 0000-0001-6379-1426
Ram AyyalaQuantitative and Computational Biology Department, USC Dana and David Dornsife College of Letters, Arts, and Sciences, University of Southern California, 1050 Childs Way, Los Angeles, CA 90089, USA.ORCID 0000-0001-7275-271X
Dhrithi DeshpandeTitus Family Department of Clinical Pharmacy, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, 1540 Alcazar Street, Los Angeles, CA 90033, USA.ORCID 0000-0003-3794-7364
Yesha M PatelTitus Family Department of Clinical Pharmacy, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, 1540 Alcazar Street, Los Angeles, CA 90033, USA.ORCID 0000-0002-4983-1222
Viorel MunteanuDepartment of Computers, Informatics and Microelectronics, Technical University of Moldova, Chisinau, 2045, Moldova.ORCID 0000-0002-4133-5945
Dumitru CiorbaDepartment of Computers, Informatics and Microelectronics, Technical University of Moldova, Chisinau, 2045, Moldova.ORCID 0000-0002-3157-5072
Andrada FiscuteanFaculty of Journalism and Communication Studies, University of Bucharest, Soseaua Panduri, nr. 90, Sector 5, 050663, Bucharest, Romania.ORCID 0000-0001-6303-5719
Mohammad VahedTitus Family Department of Clinical Pharmacy, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, 1540 Alcazar Street, Los Angeles, CA 90033, USA.ORCID 0000-0002-4721-2356
Aditya SarkarSchool of Computing and Electrical Engineering, Indian Institute of Technology Mandi, North Campus, Kamand, Mandi, Himachal Pradesh, 175005, India.ORCID 0000-0002-4496-8289
Ruiwei GuoDepartment of Pharmacology and Pharmaceutical Sciences, USC Alfred E. Mann School of Pharmacy, University of Southern California, 1985 Zonal Avenue, Room 713. Los Angeles, CA 90089-9121, USA.ORCID 0000-0002-6978-8735
Andrew MooreDaniel J. Epstein Department of Industrial and Systems Engineering, Viterbi School of Engineering, University of Southern California.ORCID 0000-0003-1457-4593
Nicholas Darci-MaherComputational and Systems Biology, University of California, Los Angeles, 580 Portola Plaza, Los Angeles, CA 90095, USA.ORCID 0000-0002-8124-030X
Nicole A NogoyGigaScience Press, L26/F, Kings Wing Plaza 2, 1 On Kwan Street, Shek Mun, N.T., Hong Kong.ORCID 0000-0002-5192-9835
Malak S AbedalthagafiDepartment of Pathology & Laboratory Medicine, Emory University Hospital, Atlanta, GA, USA.ORCID 0000-0003-1786-3366
Serghei MangulTitus Family Department of Clinical Pharmacy, USC Alfred E. Mann School of Pharmacy and Pharmaceutical Sciences, University of Southern California, 1540 Alcazar Street, Los Angeles, CA 90033, USA.ORCID 0000-0003-4770-3443

Funding

Developing robust and scalable genomics tools and databases to analyze immune receptor repertoires across diverse populationsR01AI173172 · NIAID · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ALACHKAR, HOUDA · 2023 to 2025
$2.5M
NIAID NIH HHS R01 AI173172
6 · The paper itself

Abstract

Data-driven computational analysis is becoming increasingly important in biomedical research, as the amount of data being generated continues to grow. However, the lack of practices of sharing research outputs, such as data, source code and methods, affects transparency and reproducibility of studies, which are critical to the advancement of science. Many published studies are not reproducible due to insufficient documentation, code, and data being shared. We conducted a comprehensive analysis of 453 manuscripts published between 2016-2021 and found that 50.1% of them fail to share the analytical code. Even among those that did disclose their code, a vast majority failed to offer additional research outputs, such as data. Furthermore, only one in ten papers organized their code in a structured and reproducible manner. We discovered a significant association between the presence of code availability statements and increased code availability (p=2.71×10

Identifiers

PMID37609176
PMCPMC10441317

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.