Evidence map›Paper›PMID 37609140›Full record

ArticlebioRxiv : the preprint server for biology2023

Limitations of fluorescent timer protein maturation kinetics to isolate transcriptionally synchronized cortically differentiating human pluripotent stem cells.

Manuel Peter, Seth Shipman, Jeffrey D Macklis

Open access · greenAbstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Manuel PeterDepartment of Stem Cell and Regenerative Biology, and Center for Brain Science, Harvard University, Cambridge, MA, USA.
Seth ShipmanDepartment of Stem Cell and Regenerative Biology, and Center for Brain Science, Harvard University, Cambridge, MA, USA.
Jeffrey D MacklisDepartment of Stem Cell and Regenerative Biology, and Center for Brain Science, Harvard University, Cambridge, MA, USA.
Harvard University · USGladstone Institutes · US

Funding

Subcellular RNA-Proteome Mapping in Subtype- and Circuit-Specific Growth Cones: Development, Cell Biology, Disease, and RegenerationDP1NS106665 · NINDS · HARVARD UNIVERSITY · PI MACKLIS, JEFFREY D · 2017 to 2021
$5.9M
Molecular Controls over Neurogenesis, Subtype Development, and Diversity of Cortical Output Projection NeuronsR01NS045523 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI MACKLIS, JEFFREY D · 2002 to 2020
$5.4M
Molecular Development and Diversity of Callosal Projection NeuronsR01NS104055 · NINDS · HARVARD UNIVERSITY · PI MACKLIS, JEFFREY D · 2020 to 2024
$1.9M
Molecular Mechanisms of CTIP2 Function in Corticospinal Motor Neuron DevelopmentR01NS075672 · NINDS · HARVARD UNIVERSITY · PI MACKLIS, JEFFREY D · 2012 to 2016
$1.8M
Cortico-Spinal Repopulation from Precursors for RepairR01NS049553 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI MACKLIS, JEFFREY D · 2004 to 2007
$1.6M
NINDS NIH HHS DP1 NS106665NINDS NIH HHS R01 NS045523NINDS NIH HHS R01 NS049553NINDS NIH HHS R01 NS075672NINDS NIH HHS R01 NS104055
6 · The paper itself

Abstract

Differentiation of human pluripotent stem cells (hPSC) into distinct neuronal populations holds substantial potential for disease modeling

Identifiers

PMID37609140
PMCPMC10441295
OpenAlexW4385629006

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.