Evidence map›Paper›PMID 37609019›Full record

ArticleIndian journal of orthopaedics2023

Artificial Bone Graft Substitutes for Curettage of Benign and Low-Grade Malignant Bone Tumors: Clinical and Radiological Experience with Cerasorb.

Ulrike Susanne Wittig, Jörg Friesenbichler, Bernadette Liegl-Atzwanger, Jasminka Igrec, Dimosthenis Andreou, Andreas Leithner, Susanne Scheipl

Open access · hybridAbstract read
In one paragraph

Article in Indian journal of orthopaedics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ulrike Susanne WittigDepartment of Orthopaedics and Trauma, Medical University of Graz, Auenbruggerplatz 5, Graz, Austria.ORCID 0000-0002-9415-1728
Jörg FriesenbichlerDepartment of Orthopaedics and Trauma, Medical University of Graz, Auenbruggerplatz 5, Graz, Austria.
Bernadette Liegl-AtzwangerDiagnostic and Research Center for Molecular Biomedicine, Diagnostic and Research Center for Pathology, Medical University of Graz, Graz, Austria.
Jasminka IgrecDivision of General Radiology, Department of Radiology, Medical University of Graz, Graz, Austria.
Dimosthenis AndreouDepartment of Orthopaedics and Trauma, Medical University of Graz, Auenbruggerplatz 5, Graz, Austria.
Andreas LeithnerDepartment of Orthopaedics and Trauma, Medical University of Graz, Auenbruggerplatz 5, Graz, Austria.
Susanne ScheiplDepartment of Orthopaedics and Trauma, Medical University of Graz, Auenbruggerplatz 5, Graz, Austria.
Medical University of Graz · AT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Artificial bone graft substitutes (ABGS) for curettage of bone tumors are becoming increasingly popular. The aim of this retrospective analysis was to determine the efficacy of the ABGS Cerasorb (Curasan-AG, Kleinostheim, Germany), a beta-tricalcium phosphate (beta-TCP), concerning resorption profile, bone healing, and remodeling after surgery and to evaluate potential complications. Methods: Forty-three patients suffering from benign and low-grade malignant bone tumors were treated with curettage and refilling of the bony cavity using the ABGS Cerasorb between 2018 and 2021 and included in the final analysis. Clinical follow-up exams with X-rays in two planes were performed 6 weeks, 3 months, 6 months, and 1 year after surgery. Results: After a mean follow-up period of 14.6 months, radiological consolidation following curettage was observed in all patients. Total resorption was observed in 16.3% of patients; in the other 83.7%, resorption was partial. In four patients, of whom two had a tumor in the distal femur and two in the humeral diaphysis, fractures occurred within 6 weeks after primary surgery. Conclusion: In conclusion, the beta-TCP Cerasorb seems to be a reliable bone graft substitute with low complication rates and is a suitable alternative to autologous bone grafts or allografts. Nonetheless, it shows a tendency of delayed resorption. Level of Evidence: III; retrospective cohort study.

Indexed as

ABGSArtificial bone graft substitutesBone tumorsCurettage

Identifiers

PMID37609019
PMCPMC10441831
OpenAlexW4381804481

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.