Evidence map›Paper›PMID 37608915›Full record

ArticleOpen forum infectious diseases2023

Efficacy of Minocycline for the Treatment of

Emily J Clarke, Lenka A Vodstrcil, Erica L Plummer, Ivette Aguirre, Ranjit S Samra, Christopher K Fairley, Eric P F Chow, Catriona S Bradshaw

Open access · goldAbstract read
In one paragraph

Article in Open forum infectious diseases, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 18 citations in OpenAlex.

  1. Case Report: First In-Human Report of Cure of RefractoryOpen forum infectious diseases · 2026
    Article
  2. Treatment Approaches for RefractoryOpen forum infectious diseases · 2026
    Article
  3. Article
  4. Mycoplasma Genitalium - Where are we at?Current HIV/AIDS reports · 2025
    Review
  5. Article
  6. Review
  7. Prevalence of Site-SpecificInfection and drug resistance · 2025
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Emily J ClarkeMelbourne Sexual Health Centre, Alfred Health, Carlton, Victoria, Australia.ORCID https://orcid.org/0009-0005-3082-9455
Lenka A VodstrcilMelbourne Sexual Health Centre, Alfred Health, Carlton, Victoria, Australia.ORCID https://orcid.org/0000-0003-3679-9195
Erica L PlummerMelbourne Sexual Health Centre, Alfred Health, Carlton, Victoria, Australia.ORCID https://orcid.org/0000-0001-5710-2671
Ivette AguirreMelbourne Sexual Health Centre, Alfred Health, Carlton, Victoria, Australia.
Ranjit S SamraMelbourne Sexual Health Centre, Alfred Health, Carlton, Victoria, Australia.ORCID https://orcid.org/0009-0007-6754-4255
Christopher K FairleyMelbourne Sexual Health Centre, Alfred Health, Carlton, Victoria, Australia.
Eric P F ChowMelbourne Sexual Health Centre, Alfred Health, Carlton, Victoria, Australia.
Catriona S BradshawMelbourne Sexual Health Centre, Alfred Health, Carlton, Victoria, Australia.ORCID https://orcid.org/0000-0002-6643-5678
Melbourne Sexual Health Centre · AUThe University of Melbourne · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: High levels of macrolide resistance and increasing fluoroquinolone resistance are making Methods: We evaluated minocycline 100 mg twice daily for 14 days at Melbourne Sexual Health Centre (MSHC). Microbial cure was defined as a negative test of cure within 14-90 days after completing minocycline. The proportion cured and 95% confidence intervals (CIs) were calculated, and logistic regression was used to explore factors associated with treatment failure. We pooled data from the current study with a prior adjacent case series of patients with Results: Minocycline cured 60 of 90 (67% [95% CI, 56%-76%]) infections. Adherence was high (96%) and side effects were mild and self-limiting. No demographic or clinical characteristics were associated with minocycline failure in regression analyses. In the pooled analyses of 123 patients, 83 (68% [95% CI, 58%-76%]) were cured following minocycline. Conclusions: Minocycline cured 68% of macrolide-resistant

Indexed as

antibacterial agentsminocyclinemoxifloxacinMycoplasma genitaliumsexually transmitted infections

Identifiers

PMID37608915
PMCPMC10442060
OpenAlexW4385754833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.