Evidence map›Paper›PMID 37608858›Full record

ArticleOTA international : the open access journal of orthopaedic trauma2021

Biomechanical models: key considerations in study design.

Peter Augat, Michael W Hast, Geoffrey Schemitsch, Mark Heyland, Adam Trepczynski, Edoardo Borgiani, Gabriele Russow, Sven Märdian, Georg N Duda, Marianne Hollensteiner and 2 more

Abstract read
In one paragraph

Article in OTA international : the open access journal of orthopaedic trauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

  1. Simulated gastrocnemius traction alters interfragmentary motion in Hoffa fracture fixation.European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2025
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  13. Lower-limb internal loading and potential consequences for fracture healing.Frontiers in bioengineering and biotechnology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Peter AugatInstitute for Biomechanics, Berufsgenossenschaftliche Unfallklinik Murnau, Murnau, Germany.
Michael W HastBiedermann Lab for Orthopaedic Research, University of Pennsylvania, Philadelphia, PA.
Geoffrey SchemitschFaculty of Medicine, University of Toronto, Toronto, Ontario, Canada.
Mark HeylandJulius Wolff Institute for Biomechanics and Musculoskeletal Regeneration, Berlin Institute of Health (BIH).
Adam TrepczynskiJulius Wolff Institute for Biomechanics and Musculoskeletal Regeneration, Berlin Institute of Health (BIH).
Edoardo BorgianiJulius Wolff Institute for Biomechanics and Musculoskeletal Regeneration, Berlin Institute of Health (BIH).
Gabriele RussowJulius Wolff Institute for Biomechanics and Musculoskeletal Regeneration, Berlin Institute of Health (BIH).
Sven MärdianCenter for Musculoskeletal Surgery, Charité - Universitätsmedizin, Berlin, Berlin, Germany.
Georg N DudaJulius Wolff Institute for Biomechanics and Musculoskeletal Regeneration, Berlin Institute of Health (BIH).
Marianne HollensteinerInstitute for Biomechanics, Berufsgenossenschaftliche Unfallklinik Murnau, Murnau, Germany.
Michael BottlangBiomechanics Laboratory, Legacy Research Institute, Portland, OR.
Emil H SchemitschDepartment of Surgery, University of Western Ontario, London, Ontario, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This manuscript summarizes presentations of a symposium on key considerations in design of biomechanical models at the 2019 Basic Science Focus Forum of the Orthopaedic Trauma Association. The first section outlines the most important characteristics of a high-quality biomechanical study. The second section considers choices associated with designing experiments using finite element modeling versus synthetic bones versus human specimens. The third section discusses appropriate selection of experimental protocols and finite element analyses. The fourth section considers the pros and cons of use of biomechanical research for implant design. Finally, the fifth section examines how results from biomechanical studies can be used when clinical evidence is lacking or contradictory. When taken together, these presentations emphasize the critical importance of biomechanical research and the need to carefully consider and optimize models when designing a biomechanical study.

Indexed as

biomechanical studyexperimental protocolsfinite element modelingimplant designsynthetic bones

Identifiers

PMID37608858
PMCPMC10441683

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.