ArticleOTA international : the open access journal of orthopaedic trauma2021
The induced membrane technique for bone defects: Basic science, clinical evidence, and technical tips.
Article in OTA international : the open access journal of orthopaedic trauma, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed, 13 citations in OpenAlex.
- Fracture healing: from molecular and cellular mechanisms to therapeutic strategies.Signal transduction and targeted therapy · 2026Review
- [Mechanism of actions and reflections of Masquelet induced membrane technique in diabetic wound].Zhonghua shao shang yu chuang mian xiu fu za zhi · 2026Review
- Clinical efficacy of Masquelet technique in the treatment of tibial and fibular bone defects caused by severe gunshot wounds.Frontiers in medicine · 2026Article
- Outcomes of Masquelet technique combined with gentamicin-cement-coated rigid nails in the treatment of infected bone defects: A retrospective review.Journal of clinical orthopaedics and trauma · 2025Article
- Co-Delivery of Ca-MOF and Mg-MOF Using Nanoengineered Hydrogels to Promote In Situ Mineralization and Bone Defect Repair: In Vitro and In Vivo Analysis.Advanced healthcare materials · 2025Article
- Modern Approaches and Emerging Biological Therapies to Treat Fracture Nonunion.Pharmaceutics · 2025Review
- Review
- The Use of the Masquelet Technique in the Treatment of Pathological Distal Third Femoral Fracture Secondary to Chronic Osteomyelitis.Life (Basel, Switzerland) · 2025Article
- Unique Case of Accelerated Bone Growth Precipitating a One-Stage Masquelet: A Case Report.Journal of orthopaedic case reports · 2024Article
- Management of Infected Segmental Bone Defects with Antibiotic-Cement-Coated Nails in the First Stage of the Masquelet Technique. Implantation and Removal of the Cement Spacer around the Nail: A Technical Note.The archives of bone and joint surgery · 2024Article
- In situ forming biomaterials as muscle void fillers for the provisional treatment of volumetric muscle loss injuries.Materials today. Bio · 2023Article
Corrections and comments
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Authors and funding
8 authors at 6 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The clinical management of large bone defects continues to be a difficult clinical problem to manage for treating surgeons. The induced membrane technique is a commonly employed strategy to manage these complex injuries and achieve bone union. Basic science and clinical evidence continue to expand to address questions related to the biology of the membrane and how interventions may impact clinical outcomes. In this review, we discuss the basic science and clinical evidence for the induced membrane technique as well as provide indications for the procedure and technical tips for performing the induced membrane technique.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.