Evidence map›Paper›PMID 37608585›Full record

Observational studyTechnology in cancer research & treatment

Percutaneous Application of High Power Microwave Ablation With 150 W for the Treatment of Tumors in Lung, Liver, and Kidney: A Preliminary Experience.

Carolina Lanza, Serena Carriero, Velio Ascenti, Jacopo Tintori, Francesco Ricapito, Roberto Lavorato, Pierpaolo Biondetti, Salvatore Alessio Angileri, Filippo Piacentino, Federico Fontana and 3 more

Open access · goldAbstract readObservational Study
In one paragraph

Observational study in Technology in cancer research & treatment. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 9 citations in OpenAlex.

  1. Microwave Ablation for Granulomatous Lobular Mastitis: A Narrative Review.Medical science monitor : international medical journal of experimental and clinical research · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Carolina LanzaPostgraduate School in Radiodiagnostics, Università degli Studi di Milano, Milan, Italy.ORCID 0000-0002-8286-1562
Serena CarrieroPostgraduate School in Radiodiagnostics, Università degli Studi di Milano, Milan, Italy.
Velio AscentiPostgraduate School in Radiodiagnostics, Università degli Studi di Milano, Milan, Italy.ORCID 0000-0001-8041-4075
Jacopo TintoriPostgraduate School in Radiodiagnostics, Università degli Studi di Milano, Milan, Italy.
Francesco RicapitoPostgraduate School in Radiodiagnostics, Università degli Studi di Milano, Milan, Italy.
Roberto LavoratoDiagnostic and Interventional Radiology Department, IRCCS Ca' Granda Fondazione Ospedale Maggiore Policlinico, Milan, Italy.
Pierpaolo BiondettiDiagnostic and Interventional Radiology Department, IRCCS Cà Granda Fondazione Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milan, Italy.
Salvatore Alessio AngileriDiagnostic and Interventional Radiology Department, IRCCS Cà Granda Fondazione Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milan, Italy.
Filippo PiacentinoDiagnostic and Interventional Radiology Unit, ASST Settelaghi, Varese, Italy.
Federico FontanaDiagnostic and Interventional Radiology Unit, ASST Settelaghi, Varese, Italy.
Massimo VenturiniDiagnostic and Interventional Radiology Unit, ASST Settelaghi, Varese, Italy.
Anna Maria IerardiDiagnostic and Interventional Radiology Department, IRCCS Cà Granda Fondazione Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milan, Italy.
Gianpaolo CarrafielloDiagnostic and Interventional Radiology Department, IRCCS Cà Granda Fondazione Ospedale Maggiore Policlinico, Università degli Studi di Milano, Milan, Italy.
University of Milan · ITUniversity of Insubria · ITFondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe aim of this study is to evaluate the feasibility, safety, and short-term effectiveness of a high-power (150 W) microwave ablation (MWA) device for tumor ablation in the lung, liver, and kidney.

methodsBetween December 2021 and June 2022, patients underwent high-power MWA for liver, lung, and kidney tumors. A retrospective observational study was conducted in accordance with the Declaration of Helsinki. The MWA system utilized a 150-W, 2.45-GHz microwave generator (Emprint™ HP Ablation System, Medtronic). The study assessed technical success, safety, and effectiveness, considering pre- and post-treatment diameter and volume, lesion location, biopsy and/or cone beam computed tomography (CBCT) usage, MWA ablation time, MWA power, and dose-area product (DAP).

resultsFrom December 2021 to June 2022, 16 patients were enrolled for high-power MWA. Treated lesions included hepatocellular carcinoma (10), liver metastasis from colon cancer (1), liver metastasis from pancreatic cancer (1), squamous cell lung carcinoma (2), renal cell carcinoma (1), and renal oncocytoma (1). Technical success rate was 100%. One grade 1 complication (6.25%) was reported according to CIRSE classification. Overall effectiveness was 92.8%. Pre- and post-treatment mean diameters for liver lesions were 19.9 mm and 37.5 mm, respectively; for kidney lesions, 34 mm and 35 mm; for lung lesions, 29.5 mm and 31.5 mm. Pre- and post-treatment mean volumes for liver lesions were 3.4 ml and 24 ml, respectively; for kidney lesions, 8.2 ml and 20.5 ml; for lung lesions, 10.2 ml and 32.7 ml. The mean ablation time was 48 minutes for liver, 42.5 minutes for lung, and 42.5 minutes for renal ablation. The mean DAP for all procedures was 40.83 Gcm

conclusionThis preliminary study demonstrates the feasibility, safety, and effectiveness of the new 150 W MWA device. Additionally, it shows reduced ablation times for large lesions.

Indexed as

Carcinoma, HepatocellularCatheter AblationLiver NeoplasmsHumansKidneyLungMicrowavesRetrospective StudiesTreatment Outcome150 Whigh powerkidneyliverlungmicrowave ablationthermal ablationtumor

Identifiers

PMID37608585
PMCPMC10467382
OpenAlexW4386083952

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.