Evidence map›Paper›PMID 37608358›Full record

ArticleBMC pregnancy and childbirth2023

Building a predictive model of low birth weight in low- and middle-income countries: a prospective cohort study.

Jackie K Patterson, Vanessa R Thorsten, Barry Eggleston, Tracy Nolen, Adrien Lokangaka, Antoinette Tshefu, Shivaprasad S Goudar, Richard J Derman, Elwyn Chomba, Waldemar A Carlo and 14 more

Abstract read
In one paragraph

Article in BMC pregnancy and childbirth, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

24 authors.

Jackie K PattersonDepartment of Pediatrics, University of North Carolina at Chapel Hill School of Medicine, 101 Manning Dr, Chapel Hill, NC, 27514, USA. jackie_patterson@med.unc.edu.
Vanessa R ThorstenRTI International, Research Triangle Park, Durham, NC, USA.
Barry EgglestonRTI International, Research Triangle Park, Durham, NC, USA.
Tracy NolenRTI International, Research Triangle Park, Durham, NC, USA.
Adrien LokangakaKinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Antoinette TshefuKinshasa School of Public Health, University of Kinshasa, Kinshasa, Democratic Republic of the Congo.
Shivaprasad S GoudarJawaharlal Nehru Medical College, KLE University, Belagavi, India.
Richard J DermanDepartment of Obstetrics and Gynecology, Thomas Jefferson University, Philadelphia, PA, USA.
Elwyn ChombaUniversity Teaching Hospital, Lusaka, Zambia.
Waldemar A CarloUniversity of Alabama at Birmingham, Birmingham, AL, USA.
Manolo MazariegosInstitute of Nutrition of Central America and Panama, Guatemala City, Guatemala.
Nancy F KrebsSchool of Medicine, University of Colorado, Aurora, CO, USA.
Sarah SaleemDepartment of Community Health Sciences, Aga Khan University, Karachi, Pakistan.
Robert L GoldenbergDepartment of Obstetrics and Gynecology, Columbia University, New York, NY, USA.
Archana PatelLata Medical Research Foundation, Nagpur & Datta Meghe Institute of Medical Sciences, Sawangi, India.
Patricia L HibberdSchool of Public Health, Boston University, Boston, MA, USA.
Fabian EsamaiDepartment of Child Health and Paediatrics, School of Medicine, Moi University, Eldoret, Kenya.
Edward A LiechtySchool of Medicine, Indiana University, Indianapolis, IN, USA.
Rashidul HaqueInternational Centre for Diarrhoeal Disease Research, Dhaka, Bangladesh.
Bill PetriDivision of Infectious Diseases, University of Virginia, Charlottesville, VA, USA.
Marion Koso-ThomasEunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD, USA.
Elizabeth M McClureRTI International, Research Triangle Park, Durham, NC, USA.
Carl L BoseDepartment of Pediatrics, University of North Carolina at Chapel Hill School of Medicine, 101 Manning Dr, Chapel Hill, NC, 27514, USA.
Melissa BausermanDepartment of Pediatrics, University of North Carolina at Chapel Hill School of Medicine, 101 Manning Dr, Chapel Hill, NC, 27514, USA.

Funding

Interventions to Reduce Infant Mortality and Morbidity in Low Resource SettingsUG1HD078437 · NICHD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI WALDEMAR A. CARLO FONT · 2018 to 2026
$5.6M
The University of North Carolina-Kinshasa School of Public Health Research Partnership in the Democratic Republic of Congo; a Model for Improving Women'sand Children's Health Through ResearchUG1HD076465 · NICHD · UNIV OF NORTH CAROLINA CHAPEL HILL · PI MELISSA SCHWEIKHART BAUSERMAN · 2018 to 2026
$5.6M
Boston University/Lata Medical Research Foundation Global Network for Women's Children's Health Research UnitUG1HD078439 · NICHD · BOSTON UNIVERSITY MEDICAL CAMPUS · PI Patricia L Hibberd · 2018 to 2026
$5.5M
TJU-JNMC Global Network for Women's & Children's Health Research UnitUG1HD076457 · NICHD · THOMAS JEFFERSON UNIVERSITY · PI RICHARD J DERMAN · 2018 to 2026
$5.5M
Nutrition-specific interventions to improve long-term maternal-child health outcomesUG1HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI Edwin Jose Asturias, NANCY F KREBS · 2018 to 2026
$5.4M
University of Virginia - icddr,b Research Unit for Women's and Children's Health ResearchUG1HD096730 · NICHD · UNIVERSITY OF VIRGINIA · PI Christian A Chisholm · 2018 to 2026
$5.3M
The Global Network and Preconception Maternal NutritionU10HD076474 · NICHD · UNIVERSITY OF COLORADO DENVER · PI KREBS, NANCY F · 2013 to 2017
$5.1M
Columbia University/Aga Khan University Global Network Research UnitUG1HD078438 · NICHD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI ROBERT L GOLDENBERG · 2018 to 2026
$5.1M
Global Network for Women's and Children's Health ResearchUG1HD076461 · NICHD · INDIANA UNIVERSITY INDIANAPOLIS · PI BUCHER, SHERRI LYNN, SZYLD, EDGARDO GABRIEL · 2018 to 2023
$3.2M
NICHD NIH HHS U10 HD076474NICHD NIH HHS UG1 HD076457NICHD NIH HHS UG1 HD076461NICHD NIH HHS UG1 HD076465NICHD NIH HHS UG1 HD076474NICHD NIH HHS UG1 HD078437NICHD NIH HHS UG1 HD078438NICHD NIH HHS UG1 HD078439NICHD NIH HHS UG1 HD096730
6 · The paper itself

Abstract

backgroundLow birth weight (LBW, < 2500 g) infants are at significant risk for death and disability. Improving outcomes for LBW infants requires access to advanced neonatal care, which is a limited resource in low- and middle-income countries (LMICs). Predictive modeling might be useful in LMICs to identify mothers at high-risk of delivering a LBW infant to facilitate referral to centers capable of treating these infants.

methodsWe developed predictive models for LBW using the NICHD Global Network for Women's and Children's Health Research Maternal and Newborn Health Registry. This registry enrolled pregnant women from research sites in the Democratic Republic of the Congo, Zambia, Kenya, Guatemala, India (2 sites: Belagavi, Nagpur), Pakistan, and Bangladesh between January 2017 - December 2020. We tested five predictive models: decision tree, random forest, logistic regression, K-nearest neighbor and support vector machine.

resultsWe report a rate of LBW of 13.8% among the eight Global Network sites from 2017-2020, with a range of 3.8% (Kenya) and approximately 20% (in each Asian site). Of the five models tested, the logistic regression model performed best with an area under the curve of 0.72, an accuracy of 61% and a recall of 72%. All of the top performing models identified clinical site, maternal weight, hypertensive disorders, severe antepartum hemorrhage and antenatal care as key variables in predicting LBW.

conclusionsPredictive modeling can identify women at high risk for delivering a LBW infant with good sensitivity using clinical variables available prior to delivery in LMICs. Such modeling is the first step in the development of a clinical decision support tool to assist providers in decision-making regarding referral of these women prior to delivery. Consistent referral of women at high-risk for delivering a LBW infant could have extensive public health consequences in LMICs by directing limited resources for advanced neonatal care to the infants at highest risk.

Indexed as

Child HealthDeveloping CountriesChildFemaleHumansInfantInfant, Low Birth WeightInfant, NewbornMothersPregnancyProspective StudiesWomen's HealthLow birth weightLow-income countryPretermSmall for gestational age

Identifiers

PMID37608358
PMCPMC10464177

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.