Evidence map›Paper›PMID 37608323›Full record

ArticleBMC musculoskeletal disorders2023

How safe are intra-articular corticosteroid injections to the hip?

Laura Elisa Streck, Sebastian Braun, Kimi Spilo, Cosima Sue Boettner, Marco Brenneis, Friedrich Boettner

Open access · goldAbstract read
In one paragraph

Article in BMC musculoskeletal disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Laura Elisa StreckHospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA.
Sebastian BraunHospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA.
Kimi SpiloHospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA.
Cosima Sue BoettnerHospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA.
Marco BrenneisHospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA.
Friedrich BoettnerHospital for Special Surgery, 535 East 70th Street, New York, NY, 10021, USA. boettnerf@hss.edu.
Hospital for Special Surgery · USOrthopaedic University Hospital Friedrichsheim · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIntra-articular corticosteroid injections (ICSI) are an effective symptomatic treatment for osteoarthritis of the hip. However, the safety of ICSI has been questioned and a relatively high risk for septic arthritis, rapidly progressive osteoarthritis (RPIO) and periprosthetic joint infections (PJI) in patients undergoing subsequent total hip arthroplasty (THA) have been suggested.

methodsThis is a retrospective evaluation of 682 hips that underwent ICSI with 40 mg of Triamcinolone for primary osteoarthritis of the hip. All ICSI were performed using sterile techniques, the number of ICSI in each hip and the cumulative corticosteroid dosage were assessed. Pre- and post-injection radiographs were compared to identify cases with RPIO. Native joint septic arthritis, surgical site infections and PJI were identified by chart review.

results4 hips (0.6%) developed RPIO 2-4 months following ICSI. The cumulative Triamcinolone dose was not associated with the development of RPIO (p = 0.281). 1 case was diagnosed with septic arthritis and treated with staged THA, there were no signs of infection at a 5 years follow-up. 483 hips (75.7%) underwent THA, including 199 hips with THA less than 3 months following ICSI and 181 hips with > 1 ICSI prior to THA. There were 3 superficial surgical site infections/wound dehiscence and no PJI.

conclusionThe rate of RPIO was 0.6%. The current findings suggest that if ICSI is performed under sterile conditions, the risk for septic arthritis or PJI following THA, even in patients with multiple ICSI or ICSI within 3 months prior to surgery, is minimal.

Indexed as

Arthritis, InfectiousOsteoarthritis, HipAdrenal Cortex HormonesHumansRetrospective StudiesSurgical Wound InfectionTriamcinoloneAdrenal Cortex HormonesTriamcinoloneCorticosteroidIntra-articular injectionPeriprosthetic joint infectionRapid destructive osteoarthritisRapidly progressive osteoarthritisTriamcinolone

Identifiers

PMID37608323
PMCPMC10463482
OpenAlexW4386068463

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.