Evidence map›Paper›PMID 37608249›Full record

ArticleJournal of neurodevelopmental disorders2023

Why are only some children with autism spectrum disorder misclassified by the social communication questionnaire? An empirical investigation of individual differences in sensitivity and specificity in a clinic-referred sample.

Chimei M Lee, Melody R Altschuler, Amy N Esler, Catherine A Burrows, Rebekah L Hudock

Abstract read
In one paragraph

Article in Journal of neurodevelopmental disorders, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Chimei M LeeDivision of Clinical Behavioral Neuroscience, Department of Pediatrics, University of Minnesota, 2025 E River Pkwy, Minneapolis, MN, 55414, USA. chimeil@umn.edu.ORCID http://orcid.org/0000-0001-5983-4729
Melody R AltschulerDepartment of Psychology, Berea College, 101 Chestnut St, Berea, KY, USA.
Amy N EslerDivision of Clinical Behavioral Neuroscience, Department of Pediatrics, University of Minnesota, 2025 E River Pkwy, Minneapolis, MN, 55414, USA.
Catherine A BurrowsDivision of Clinical Behavioral Neuroscience, Department of Pediatrics, University of Minnesota, 2025 E River Pkwy, Minneapolis, MN, 55414, USA.
Rebekah L HudockDivision of Clinical Behavioral Neuroscience, Department of Pediatrics, University of Minnesota, 2025 E River Pkwy, Minneapolis, MN, 55414, USA.

Funding

University of MN Building Interdisciplinary Research Careers in Women's HealthK12AR084223 · NIAMS · UNIVERSITY OF MINNESOTA · PI SHARON S ALLEN, Kristen Patricia Mark · 2023 to 2026
$2.2M
Towards equitable early identification of autism spectrum disorders in femalesK23HD112507 · NICHD · UNIVERSITY OF MINNESOTA · PI Catherine Ann Burrows · 2023 to 2026
$459k
NIAMS NIH HHS K12 AR084223NICHD NIH HHS K23 HD112507
6 · The paper itself

Abstract

backgroundThe Social Communication Questionnaire (SCQ) is a checklist for autism spectrum disorder (ASD) commonly used in research and clinical practice. While the original validation study suggested that the SCQ was an accurate ASD screener with satisfactory sensitivity and specificity, subsequent studies have yielded mixed results, with some revealing low sensitivity, low specificity, and low utility in some settings.

methodThe present study examined the psychometric properties of the SCQ as well as the individual difference characteristics of 187 individuals with and without autism spectrum disorder (ASD) who were misclassified or accurately classified by the SCQ in a clinic-referred sample.

resultsThe SCQ showed suboptimal sensitivity and specificity, regardless of age and sex. Compared to true positives, individuals classified as false positives displayed greater externalizing and internalizing problems, whereas individuals classified as false negatives displayed better social communication and adaptive skills.

conclusionsThe findings suggest that non-autistic developmental and behavioral individual difference characteristics may explain high rates of misclassification using the SCQ. Clinicians and researchers could consider using the SCQ in combination with other tools for young children with internalizing and externalizing symptoms and other more complex clinical presentations.

Indexed as

Autism Spectrum DisorderChildChild, PreschoolCommunicationHumansIndividualityPsychometricsAdaptive behaviorAutism spectrum disorderDiagnosisEarly identificationExternalizingIndividual differencesInternalizingScreeningSensitivitySocial Communication QuestionnaireSpecificity

Identifiers

PMID37608249
PMCPMC10463287

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.