SynthesisPediatric research2024
Quantitative impact of frenotomy on breastfeeding: a systematic review and meta-analysis.
Synthesis in Pediatric research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 3 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 3 syntheses or guidelines pooled it, 20 citations in OpenAlex.
- Diode Laser-Assisted Oral Frenectomy as a Modern Alternative: A Systematic Review and Meta-Analysis.Lasers in surgery and medicine · 2026Pooled it
- Lingual Frenotomy in Breastfeeding Infants: An Umbrella Review.International journal of paediatric dentistry · 2026Pooled it
- Frenectomy for ankyloglossia in children under five: a systematic review and meta-analysis on breastfeeding outcomes.International breastfeeding journal · 2025Pooled it
- Lingual frenotomy for breastfeeding difficulties: indications, surgical techniques and multidisciplinary care in infants and young children.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Review
- Maternal reported long-term outcomes of early feeding challenges from hospital discharge to early childhood.BMC pediatrics · 2026Article
- Public Perceptions of Ankyloglossia on Reddit: A Cross-Sectional Thematic and Sentiment Analysis.Laryngoscope investigative otolaryngology · 2026Article
- Ankyloglossia in Newborns: Clinical Implications and Management-A Narrative Review.Children (Basel, Switzerland) · 2026Review
- Effects of Frenulotomy on Outcomes Associated with Breastfeeding Practice.Journal of clinical medicine · 2026Article
- Effect of Nipple Shield Use on Exclusive Breastfeeding up to 6 Months in Mothers with Nipple Abnormalities: A Randomized Controlled Trial.International journal of women's health · 2026Article
- Ankyloglossia and breastfeeding self-efficacy in newborns: a birth cohort study.BMC oral health · 2025Article
- Tongue-tie diagnosis using the Lingual frenulum in newborn infants (LINNE) -scoring: A validation study.PloS one · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
backgroundSymptoms related to infant ankyloglossia/tongue-tie may deter mothers from breastfeeding, yet frenotomy is controversial.
methodsDatabases included PubMed, Embase, CINAHL, PsycINFO, Web of Science, and Google Scholar from 1961-2023. Controlled trials and cohort studies with validated measures of surgical efficacy for breastfeeding outcomes were eligible. Meta-analyses synthesized data with inverse-variance weighting to determine standardized mean differences (SMD) between pre-/postoperative scores.
resultsTwenty-one of 1568 screened studies were included. Breastfeeding self-efficacy improved significantly post-frenotomy: medium effect after 5-10 days (SMD 0.60 [95% CI: 0.48, 0.71; P < 0.001]), large effect after 1 month (SMD 0.91 [CI: 0.79, 1.04; P < 0.001]). Nipple pain decreased significantly post-frenotomy: large effect after 5-15 days (SMD -1.10 [CI: -1.49, -0.70; P < 0.001]) and 1 month (SMD -1.23 [CI: -1.79, -0.67; P = 0.002]). Frenotomy had a medium effect on infant gastroesophageal reflux severity at 1-week follow-up (SMD -0.63 [CI: -0.95, -0.31; P = 0.008]), with continued improvement at 1 month (SMD -0.41 [CI: -0.78, -0.05; P = 0.04]). From LATCH scores, breastfeeding quality improved after 5-7 days by a large SMD of 1.28 (CI: 0.56, 2.00; P = 0.01).
conclusionsProviders should offer frenotomy to improve outcomes in dyads with ankyloglossia-associated breastfeeding difficulties. PROTOCOL REGISTRATION: PROSPERO identifier CRD42022303838 . IMPACT: This systematic review and meta-analysis showed that breastfeeding self-efficacy, maternal pain, infant latch, and infant gastroesophageal reflux significantly improve after frenotomy in mother-infant dyads with breastfeeding difficulties and ankyloglossia. Providers should offer frenotomy to improve breastfeeding outcomes in symptomatic mother-infant dyads who face challenges associated with ankyloglossia.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.