ArticleScientific reports2023
Dysregulation of testis mRNA expression levels in hatchery-produced vs wild greater amberjack Seriola dumerili.
Article in Scientific reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 10 citations in OpenAlex.
- High-quality Chromosome-level genome assembly of male and female greater amberjack (Seriola dumerili).Scientific data · 2025Article
- Characteristics and Functions of Different Intestinal Segments in Juvenile Greater Amberjack (Animals : an open access journal from MDPI · 2025Article
- Spermatogenesis advancement in pre-pubertal meagre Argyrosomus regius treated with recombinant gonadotropins.Scientific reports · 2025Article
- Transcriptomic Analysis Provides New Insights into Oocyte Growth and Maturation in Greater Amberjack (Animals : an open access journal from MDPI · 2025Article
- Comparative transcriptome analysis identified genes involved in testicular development in Takifugu rubripes.Fish physiology and biochemistry · 2025Article
- Comparison of ovarian mRNA expression levels in wild and hatchery-produced greater amberjack Seriola dumerili.Scientific reports · 2024Article
Corrections and comments
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Authors and funding
13 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Reproductive dysfunctions have been recently documented in male greater amberjack Seriola dumerili caught from the wild and reared in captivity. In the present study, we compared testis transcriptome in wild fish (WILD), hatchery-produced fish with apparently normal spermatogenesis (Normal Farmed; NormalF) and hatchery-produced fish with evident reproductive dysfunction (Dysfunctional Farmed; DysF). Gene expression analysis identified 2157, 1985 and 74 differentially expressed genes (DEGs) in DysF vs WILD, NormalF vs DysF and NormalF vs WILD comparisons, respectively. In DysF, a dysregulation of several interconnected biological processes, including cell assembly, steroidogenesis and apoptosis was found. Gene enrichment of progesterone-mediated oocyte maturation, oocyte meiosis and cell cycle pathways were identified in the DysF vs NormalF comparison. Most of the DEGs involved in the enriched pathways were downregulated in DysF. The comparison of NormalF vs WILD showed that most of the DEGs were downregulated in NormalF, including a gene that encodes for a regulatory protein with a protective role in apoptosis regulation (ptpn6), indicating that spermatogenesis was dysfunctional also in the apparently "normal" hatchery-produced fish. Hence, rearing of male greater amberjack in captivity, from eggs produced by captive breeders, did not prevent the appearance of reproductive dysfunctions, and these dysfunctions involved several biological processes and metabolic pathways.
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