Evidence map›Paper›PMID 37607929›Full record

ArticleScientific data2023

A large public dataset of annotated clinical MRIs and metadata of patients with acute stroke.

Chin-Fu Liu, Richard Leigh, Brenda Johnson, Victor Urrutia, Johnny Hsu, Xin Xu, Xin Li, Susumu Mori, Argye E Hillis, Andreia V Faria

Abstract readDataset
In one paragraph

Article in Scientific data, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Chin-Fu LiuCenter for Imaging Science, Johns Hopkins University, Baltimore, MD, USA.
Richard LeighDepartment of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Brenda JohnsonDepartment of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Victor UrrutiaDepartment of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Johnny HsuDepartment of Radiology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Xin XuDepartment of Radiology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Xin LiDepartment of Radiology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Susumu MoriDepartment of Radiology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Argye E HillisDepartment of Neurology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA.
Andreia V FariaDepartment of Radiology, School of Medicine, Johns Hopkins University, Baltimore, MD, USA. afaria1@jhmi.edu.ORCID http://orcid.org/0000-0002-1673-002X

Funding

Telerehab for Aphasia (TERRA)P50DC014664 · NIDCD · UNIVERSITY OF SOUTH CAROLINA AT COLUMBIA · PI FRIDRIKSSON, JULIUS · 2016 to 2025
$25.0M
Neural Basis of Lexical Deficits in Hyperacute StrokeR01DC005375 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI Argye E. Hillis · 2002 to 2026
$11.8M
TRD 4: Platforms for multi-modal and multi-scale imaging dataP41EB031771 · NIBIB · HUGO W. MOSER RES INST KENNEDY KRIEGER · PI Hanzhang Lu, Peter CM Van Zijl · 2021 to 2026
$9.9M
The Neural Basis of Impaired Affective Prosody in Alzheimer's Disease and Frontotemporal DegenerationR01DC015466 · NIDCD · JOHNS HOPKINS UNIVERSITY · PI HILLIS, ARGYE E. · 2017 to 2021
$3.5M
NIBIB NIH HHS P41 EB031771NIDCD NIH HHS P50 DC014664NIDCD NIH HHS R01 DC005375NIDCD NIH HHS R01 DC015466
6 · The paper itself

Abstract

To extract meaningful and reproducible models of brain function from stroke images, for both clinical and research proposes, is a daunting task severely hindered by the great variability of lesion frequency and patterns. Large datasets are therefore imperative, as well as fully automated image post-processing tools to analyze them. The development of such tools, particularly with artificial intelligence, is highly dependent on the availability of large datasets to model training and testing. We present a public dataset of 2,888 multimodal clinical MRIs of patients with acute and early subacute stroke, with manual lesion segmentation, and metadata. The dataset provides high quality, large scale, human-supervised knowledge to feed artificial intelligence models and enable further development of tools to automate several tasks that currently rely on human labor, such as lesion segmentation, labeling, calculation of disease-relevant scores, and lesion-based studies relating function to frequency lesion maps.

Indexed as

Magnetic Resonance ImagingStrokeArtificial IntelligenceHumansImage Processing, Computer-AssistedMetadataPatients

Identifiers

PMID37607929
PMCPMC10444746

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.