Evidence map›Paper›PMID 37607502›Full record

ArticleAnnals of nutrition & metabolism2023

Plasma Fatty Acid Biomarkers of Dairy Consumption Are Associated with Sex-Dependent Effects on Metabolic Syndrome Components in Mexican Adolescents.

Rebeca Trejo-Reyes, Alejandra Cantoral, Hector Lamadrid-Figueroa, Larissa Betanzos-Robledo, Martha María Téllez-Rojo, Karen E Peterson, Ana Baylin, Erica C Jansen

Open access · hybridAbstract read
In one paragraph

Article in Annals of nutrition & metabolism, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Rebeca Trejo-ReyesCenter for Nutrition and Health Research, National Institute of Public Health, Cuernavaca, Mexico, rebeca.trejo@insp.edu.mx.
Alejandra CantoralHealth Department, Iberoamerican University, Mexico City, Mexico.
Hector Lamadrid-FigueroaCenter for Population Health Research, National Institute of Public Health, Cuernavaca, Mexico.
Larissa Betanzos-RobledoCenter for Nutrition and Health Research, National Institute of Public Health, Cuernavaca, Mexico.
Martha María Téllez-RojoCenter for Nutrition and Health Research, National Institute of Public Health, Cuernavaca, Mexico.
Karen E PetersonDepartment of Nutritional Sciences, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Ana BaylinDepartment of Nutritional Sciences, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Erica C JansenDepartment of Nutritional Sciences, School of Public Health, University of Michigan, Ann Arbor, Michigan, USA.
Instituto Nacional de Salud Pública · MXUniversity of Michigan–Ann Arbor · USIbero American University · MX

Funding

Strategic Vision & Impact on Environmental HealthP30ES017885 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Dana Dolinoy · 2011 to 2026
$21.3M
Pilot and Feasibility (P and F) ProgramP30DK089503 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Kanakadurga Singer · 2010 to 2026
$20.3M
Statistics and Bioinformatics Core - WangU24DK097153 · NIDDK · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI BURANT, CHARLES F · 2012 to 2017
$10.1M
Project 3: Developmental Exposures and Diet: Epigenetics of Metabolic SyndromeP01ES022844 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI HEAD, REBECCA, PADMANABHAN, VASANTHA · 2013 to 2018
$3.9M
Sleep and Circadian Rhythms in Adolescence: Epigenetic Pathways of Cardiometabolic RiskK01HL151673 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI JANSEN, ERICA CHRISTINE · 2020 to 2024
$759k
NHLBI NIH HHS K01 HL151673NIDDK NIH HHS P30 DK089503NIDDK NIH HHS U24 DK097153NIEHS NIH HHS P01 ES022844NIEHS NIH HHS P30 ES017885
6 · The paper itself

Abstract

introductionDuring adolescence, dairy product intake has shown conflicting associations with metabolic syndrome (MetS) components, which are risk factors for cardiovascular disease (CVD). This study aims to investigate the association between plasma fatty acids (FAs) C15:0, C17:0, and t-C16:1n-7, as biomarkers of dairy intake, with MetS and its components in Mexican adolescents.

methodsA sample of 311 participants from the Early Life Exposure in Mexico City to Environmental Toxicants (ELEMENT) cohort was included in this cross-sectional analysis. FA concentrations were measured in plasma as a percentage of total FA. We used quantile regression models stratified by sex to evaluate the association between FA quantiles and MetS components, adjusting for age, socioeconomic status (SES), sedentary behavior, BMI z-score, pubertal status, and energy intake.

resultsWe found significant associations between dairy biomarkers and the median of MetS variables. In females, t-C16:1n-7 was associated with a decrease of 2.97 cm in WC (Q4 vs. Q1; 95% CI: -5.79, -0.16). In males, C15:0 was associated with an increase of 5.84 mm/Hg in SBP (Q4 vs. Q1; CI: 1.82, 9.85). For HDL-C, we observed opposite associations by sex. C15:0 in males was associated with decreased HDL-C (Q3 vs. Q1: β = -4.23; 95% CI: -7.98, -0.48), while in females, C15:0 and t-C16:1n-7 were associated with increased HDL-C (Q3 vs. Q1: β = 4.75; 95% CI: 0.68, 8.82 and Q4 vs. Q1: β = 6.54; 95% CI: 2.01, 11.07), respectively. Additionally, in both sexes, different levels of C15:0, C17:0, and t-C16:1n-7 were associated with increased triglycerides (TG).

conclusionOur results suggest that adolescent dairy intake may be associated in different directions with MetS components and that associations are sex-dependent.

Indexed as

Fatty AcidsMetabolic SyndromeAdolescentBiomarkersCross-Sectional StudiesDairy ProductsDietary FatsFemaleHumansMaleMexicoRisk FactorsBiomarkersDietary FatsFatty AcidsBiomarkersCardiovascular risk factorsDairy productsHeptadecanoic acidPentadecanoic acidTrans-palmitoleic acid

Identifiers

PMID37607502
PMCPMC10614258
OpenAlexW4386084453

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.