Evidence map›Paper›PMID 37607059›Full record

ArticleJournal of virology2023

The African swine fever virus I10L protein inhibits the NF-

Xing Chen, Lian-Feng Li, Zhong-Yuan Yang, Meilin Li, Shuai Fan, Lan-Fang Shi, Zi-Yu Ren, Xue-Jing Cao, Yuhang Zhang, Shichong Han and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of virology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 1 country.

Xing Chen *International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University , Zhengzhou, Henan, China.
Lian-Feng Li *State Key Laboratory for Animal Disease Control and Prevention, National African Swine Fever Para-Reference Laboratory, National High-Containment Facilities for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences , Harbin, Heilongjiang, China.ORCID 0000-0001-9653-5533
Zhong-Yuan Yang *International Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University , Zhengzhou, Henan, China.
Meilin LiState Key Laboratory for Animal Disease Control and Prevention, National African Swine Fever Para-Reference Laboratory, National High-Containment Facilities for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences , Harbin, Heilongjiang, China.
Shuai FanInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University , Zhengzhou, Henan, China.
Lan-Fang ShiInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University , Zhengzhou, Henan, China.
Zi-Yu RenInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University , Zhengzhou, Henan, China.
Xue-Jing CaoInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University , Zhengzhou, Henan, China.
Yuhang ZhangInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University , Zhengzhou, Henan, China.
Shichong HanInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University , Zhengzhou, Henan, China.
Bo WanInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University , Zhengzhou, Henan, China.ORCID 0000-0001-7900-2831
Hua-Ji QiuState Key Laboratory for Animal Disease Control and Prevention, National African Swine Fever Para-Reference Laboratory, National High-Containment Facilities for Animal Disease Control and Prevention, Harbin Veterinary Research Institute, Chinese Academy of Agricultural Sciences , Harbin, Heilongjiang, China.ORCID 0000-0001-5791-0812
Gaiping ZhangInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University , Zhengzhou, Henan, China.
Wen-Rui HeInternational Joint Research Center of National Animal Immunology, College of Veterinary Medicine, Henan Agricultural University , Zhengzhou, Henan, China.ORCID 0000-0002-4955-3357
Henan Agricultural University · CNChinese Academy of Agricultural Sciences · CNZhengzhou University · CN

Funding

MOST | National Natural Science Foundation of China (NSFC) 31941001MOST | National Natural Science Foundation of China (NSFC) 32002278MOST | National Natural Science Foundation of China (NSFC) 32072855MOST | National Natural Science Foundation of China (NSFC) 32102655MOST | National Natural Science Foundation of China (NSFC) 32272987
6 · The paper itself

Abstract

Proinflammatory factors play important roles in the pathogenesis of African swine fever virus (ASFV), which is the causative agent of African swine fever (ASF), a highly contagious and severe hemorrhagic disease. Efforts in the prevention and treatment of ASF have been severely hindered by knowledge gaps in viral proteins responsible for modulating host antiviral responses. In this study, we identified the I10L protein (pI10L) of ASFV as a potential inhibitor of the TNF-

Indexed as

African Swine FeverAfrican Swine Fever VirusI-kappa B KinaseNF-kappa BSignal TransductionViral ProteinsAnimalsHEK293 CellsHumansInterleukin-1betaMacrophages, AlveolarPhosphorylationSwineTumor Necrosis Factor-alphaUbiquitinationI-kappa B KinaseInterleukin-1betaNF-kappa BTumor Necrosis Factor-alphaViral ProteinsAfrican swine fever virusI10L proteinIKKβinflammatory response

Identifiers

PMID37607059
PMCPMC10537781
OpenAlexW4386031615

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.