Evidence map›Paper›PMID 37607057›Full record

ArticleInfection and immunity2023

Pore-forming activity of

Shuying Xu, Devons Mo, Fatima Z Rizvi, Juan P Rosa, Jorge Ruiz, Shumin Tan, Rodney K Tweten, John M Leong, Walter Adams

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Article
  6. Mucosal immunotherapy targeting APC in lung disease.Journal of inflammation (London, England) · 2025
    Review
  7. Understanding the mechanisms ofTissue barriers · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Biological puzzles solved by usingJournal of bacteriology · 2024
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Shuying XuDepartment of Molecular Biology and Microbiology, Tufts University , Boston, Massachusetts, USA.ORCID 0000-0003-4572-8663
Devons MoDepartment of Biological Sciences, San Jose State University , San Jose, California, USA.
Fatima Z RizviDepartment of Biological Sciences, San Jose State University , San Jose, California, USA.
Juan P RosaDepartment of Molecular Biology and Microbiology, Tufts University , Boston, Massachusetts, USA.
Jorge RuizDepartment of Molecular Biology and Microbiology, Tufts University , Boston, Massachusetts, USA.
Shumin TanDepartment of Molecular Biology and Microbiology, Tufts University , Boston, Massachusetts, USA.
Rodney K TwetenDepartment of Microbiology and Immunology, University of Oklahoma Health Sciences Center , Oklahoma, Oklahoma, USA.
John M LeongDepartment of Molecular Biology and Microbiology, Tufts University , Boston, Massachusetts, USA.
Walter AdamsDepartment of Molecular Biology and Microbiology, Tufts University , Boston, Massachusetts, USA.ORCID 0000-0002-2979-1382
Tufts University · USUniversity of California, Santa Cruz · USUniversity of Oklahoma Health Sciences Center · US

Funding

Training in Education and Critical Research SkillsK12GM074869 · NIGMS · TUFTS UNIVERSITY BOSTON · PI MOORE, CLAIRE L · 2006 to 2017
$8.5M
Pore Formation by Cholesterol Dependent CytolysinsR37AI037657 · NIAID · UNIVERSITY OF OKLAHOMA HLTH SCIENCES CTR · PI TWETEN, RODNEY K. · 2016 to 2025
$4.8M
Microbial and Host Factors that Promote Epithelial Disruption and S. pneumoniae Transit out of the LungSC2GM141988 · NIGMS · SAN JOSE STATE UNIVERSITY · PI ADAMS, WALTER ISAIAH · 2021 to 2023
$440k
NIAID NIH HHS R37 AI037657NIGMS NIH HHS K12 GM074869NIGMS NIH HHS SC2 GM141988
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Adherens JunctionsStreptococcus pneumoniaeAnimalsBacterial ProteinsCadherinsMiceStreptolysinsBacterial ProteinsCadherinsplY protein, Streptococcus pneumoniaeStreptolysinsairway mucosal barriercholesterol-dependent cytolysinE-cadherinepithelial cell junctionneutrophils

Identifiers

PMID37607057
PMCPMC10501216
OpenAlexW4386031501

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.