Evidence map›Paper›PMID 37606751›Full record

ArticleBiotechnology letters2023

Antimicrobial activity of thermophilin 110 against the opportunistic pathogen Cutibacterium acnes.

John A Renye, Mayra A Mendez-Encinas, Andre K White, Amanda L Miller, Michael J McAnulty, Madhav P Yadav, Arland T Hotchkiss, Giselle K P Guron, Adam M Oest, Karla G Martinez-Robinson and 1 more

Abstract read
PubMed Publisher
In one paragraph

Article in Biotechnology letters, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Integrating Bacteriocins and Biofilm-Degrading Enzymes to EliminateInternational journal of molecular sciences · 2025
    Article
  3. Review
  4. BlpU is a broad-spectrum bacteriocin inFrontiers in microbiology · 2024
    Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 3 countries.

John A RenyeDairy and Functional Foods Research Unit, Agricultural Research Service, USDA, 600 E. Mermaid Lane, Wyndmoor, PA, 19038, USA. john.renye@usda.gov.ORCID http://orcid.org/0000-0001-6294-6422
Mayra A Mendez-Encinas *Department of Chemical Biological and Agropecuary Sciences, University of Sonora, Avenida Universidad e Irigoyen, S/N, 83621, Caborca, SON, Mexico.
Andre K WhiteDairy and Functional Foods Research Unit, Agricultural Research Service, USDA, 600 E. Mermaid Lane, Wyndmoor, PA, 19038, USA.
Amanda L MillerDairy and Functional Foods Research Unit, Agricultural Research Service, USDA, 600 E. Mermaid Lane, Wyndmoor, PA, 19038, USA.
Michael J McAnultyDairy and Functional Foods Research Unit, Agricultural Research Service, USDA, 600 E. Mermaid Lane, Wyndmoor, PA, 19038, USA.
Madhav P YadavSustainable Biofuels and Co-Products Foods Research Unit, Agricultural Research Service, USDA, 600 E. Mermaid Lane, Wyndmoor, PA, 19038, USA.
Arland T HotchkissDairy and Functional Foods Research Unit, Agricultural Research Service, USDA, 600 E. Mermaid Lane, Wyndmoor, PA, 19038, USA.
Giselle K P GuronDairy and Functional Foods Research Unit, Agricultural Research Service, USDA, 600 E. Mermaid Lane, Wyndmoor, PA, 19038, USA.
Adam M OestDairy and Functional Foods Research Unit, Agricultural Research Service, USDA, 600 E. Mermaid Lane, Wyndmoor, PA, 19038, USA.
Karla G Martinez-RobinsonResearch Center for Food and Development, A.C. Carretera Gustavo E. Astiazaran Rosas 46, 83304, Hermosillo, SON, Mexico.
Elizabeth Carvajal-MillanResearch Center for Food and Development, A.C. Carretera Gustavo E. Astiazaran Rosas 46, 83304, Hermosillo, SON, Mexico.
Agricultural Research Service · USUniversidad de Sonora · MX

Funding

Agricultural Research Service Project 8072-41000-114
6 · The paper itself

Abstract

objectiveThermophilin 110, a bacteriocin produced by Streptococcus thermophilus B59671, inhibited planktonic growth and biofilm formation of Cutibacterium acnes, a commensal skin bacterium associated with the inflammatory disease, acne vulgaris, and more invasive deep tissue infections.

resultsThermophilin 110 prevented planktonic growth of C. acnes at a concentration ≥ 160 AU mL

conclusionsThermophilin 110 has potential as an antimicrobial for preventing C. acnes infections and further optimization of SA and AX gel formulations could allow them to serve as delivery systems for bacteriocins or bacteriocin-producing probiotics.

Indexed as

BacteriocinsSkinAlginatesCell AggregationHydrogelsAlginatesBacteriocinsHydrogelsBacteriocinBiofilmCutibacterium acnesStreptococcus thermophilus

Identifiers

PMID37606751
OpenAlexW4386046345

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.