Evidence map›Paper›PMID 37606737›Full record

ArticleNeurocritical care2023

Common Data Elements for Disorders of Consciousness: Recommendations from the Electrophysiology Working Group.

Elizabeth E Carroll, Caroline Der-Nigoghossian, Ayham Alkhachroum, Brian Appavu, Emily Gilmore, Julie Kromm, Benjamin Rohaut, Mario Rosanova, Jacobo Diego Sitt, Jan Claassen and 1 more

Erratum issuedAbstract read
In one paragraph

Article in Neurocritical care, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Observational
  5. CDEMapper: enhancing National Institutes of Health common data element use with large language models.Journal of the American Medical Informatics Association : JAMIA · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

Elizabeth E CarrollDepartment of Neurology, Columbia University Medical Center, 177 Fort Washington Avenue, MHB 8 Center, Room 300, New York, NY, 10032, USA.
Caroline Der-NigoghossianNewYork-Presbyterian Hospital, New York, NY, USA.
Ayham AlkhachroumDepartment of Neurology, University of Miami, Miami, FL, USA.
Brian AppavuBarrow Neurological Institute at Phoenix Children's Hospital, Phoenix, AZ, USA.
Emily GilmoreDivisions of Neurocritical Care and Emergency Neurology and Epilepsy, Department of Neurology, Yale University School of Medicine, New Haven, CT, USA.
Julie KrommDepartments of Critical Care Medicine and Clinical Neurosciences, University of Calgary, Calgary, AB, Canada.
Benjamin RohautSorbonne Université, Institut du Cerveau - Paris Brain Institute - ICM, Inserm, Centre national de la recherche scientifique, Assistance Publique-Hôpitaux de Paris, Neurosciences, Hôpital de La Pitié Salpêtrière, Paris, France.
Mario RosanovaDepartment of Biomedical and Clinical Sciences, University of Milan, Milan, Italy.
Jacobo Diego SittParis Brain Institute (ICM), Centre national de la recherche scientifique, Paris, France.
Jan ClaassenDepartment of Neurology, Columbia University Medical Center, 177 Fort Washington Avenue, MHB 8 Center, Room 300, New York, NY, 10032, USA. jc1439@columbia.edu.ORCID 0000-0002-5893-8531
Curing Coma Campaign and its Contributing Members

Funding

Miami Clinical and Translational Science InstituteUL1TR002736 · NCATS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRASQUILLO, OLVEEN, KOBETZ, ERIN N · 2018 to 2022
$23.2M
Intracranial multimodal physiological monitoring in acute brain injuryUG3NS123307 · NINDS · YALE UNIVERSITY · PI SPENCER, DENNIS D, ZAVERI, HITTEN P · 2022 to 2024
$5.6M
RECONFIG - REcovery of CONsciousness Following Intracerebral hemorrhaGeR01NS106014 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CLAASSEN, JAN · 2019 to 2023
$3.6M
ELECTRO-BOOST: Electroencephalography for cerebral trauma recovery and oxygenationR01NS117904 · NINDS · YALE UNIVERSITY · PI DING, KAN, GILMORE, EMILY · 2020 to 2025
$3.2M
MUSICA - MUsic and Speech Induced Cerebral ActivationK23NS126577 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI Ayham Alkhachroum · 2022 to 2026
$910k
COVERT– COvert Volitional Eye Response TestR21NS128326 · NINDS · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI ALKHACHROUM, AYHAM, CLAASSEN, JAN · 2022 to 2023
$428k
BAsIC - Brain-computer-interface practical Application in the Intensive Care unit: a pilot studyR03NS112760 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI CLAASSEN, JAN · 2019 to 2020
$162k
NCATS NIH HHS UL1 TR002736NINDS NIH HHS K23 NS126577NINDS NIH HHS NS106014NINDS NIH HHS NS112760NINDS NIH HHS NS117904NINDS NIH HHS NS123307NINDS NIH HHS NS126577NINDS NIH HHS NS128326NINDS NIH HHS R01 NS106014NINDS NIH HHS R01 NS117904NINDS NIH HHS R03 NS112760NINDS NIH HHS R21 NS128326NINDS NIH HHS UG3 NS123307
6 · The paper itself

Abstract

backgroundElectroencephalography (EEG) has long been recognized as an important tool in the investigation of disorders of consciousness (DoC). From inspection of the raw EEG to the implementation of quantitative EEG, and more recently in the use of perturbed EEG, it is paramount to providing accurate diagnostic and prognostic information in the care of patients with DoC. However, a nomenclature for variables that establishes a convention for naming, defining, and structuring data for clinical research variables currently is lacking. As such, the Neurocritical Care Society's Curing Coma Campaign convened nine working groups composed of experts in the field to construct common data elements (CDEs) to provide recommendations for DoC, with the main goal of facilitating data collection and standardization of reporting. This article summarizes the recommendations of the electrophysiology DoC working group.

methodsAfter assessing previously published pertinent CDEs, we developed new CDEs and categorized them into "disease core," "basic," "supplemental," and "exploratory." Key EEG design elements, defined as concepts that pertained to a methodological parameter relevant to the acquisition, processing, or analysis of data, were also included but were not classified as CDEs.

resultsAfter identifying existing pertinent CDEs and developing novel CDEs for electrophysiology in DoC, variables were organized into a framework based on the two primary categories of resting state EEG and perturbed EEG. Using this categorical framework, two case report forms were generated by the working group.

conclusionsAdherence to the recommendations outlined by the electrophysiology working group in the resting state EEG and perturbed EEG case report forms will facilitate data collection and sharing in DoC research on an international level. In turn, this will allow for more informed and reliable comparison of results across studies, facilitating further advancement in the realm of DoC research.

Indexed as

Biomedical ResearchCommon Data ElementsConsciousness DisordersData CollectionElectrophysiologyHumansComaCommon data elementsConsciousnessElectrophysiology

Identifiers

PMID37606737
PMCPMC11938239

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.