Observational studyEuropean journal of pediatrics2023
Thyroid volume is the key predictor of hyperthyroidism remission after radioactive iodine therapy in pediatric patients.
Observational study in European journal of pediatrics, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 6 citations in OpenAlex.
- Radioiodine or thyroidectomy in children and adolescents with Graves' disease: a structured literature review of efficacy and safety.Clinical pediatric endocrinology : case reports and clinical investigations : official journal of the Japanese Society for Pediatric Endocrinology · 2026Review
- Thyroid/parathyroid function and fluoride: role of mitochondrial DNA and SOD genetic variations.Journal of endocrinological investigation · 2026Article
- Novel triple-drug regimen for preoperative optimization in giant Graves' disease: a prospective efficacy and safety trial.Gland surgery · 2026Article
- Sex-Related Differences in Risk Factors Associated With Nonhealing or Recurrence of Hyperthyroidism in Patients With Graves' Disease Treated With Radioactive Iodine.Health care science · 2025Article
- A Belgian single centre outcome study of radioiodine treatment in adolescents with Graves' disease.Scientific reports · 2024Article
- Article
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Authors and funding
6 authors at 2 institutions in 1 country.
Funding
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Abstract
Graves' disease (GD) is the leading cause of hyperthyroidism in pediatric patients. Radioactive iodine therapy (RAIT) is widely used to treat GD. However, it is still unclear exactly what determines the efficacy of RAIT in childhood and adolescence. The objective of our study was to reveal the most significant predictors of the efficacy of RAIT in pediatric GD patients. A single-center prospective observational exploratory study enrolled 144 pediatric patients (124 females and 20 males) between 8 and 18 years of age who underwent dosimetry-guided RAIT for GD for the first time. The estimated parameters included sex, age, thyroid volume, thyroid stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4), thyroid-stimulating hormone receptor antibodies (TRABs) at baseline and 12 months after RAIT, 10- to 20-min
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