Evidence map›Paper›PMID 37606697›Full record

ArticleInternational journal of colorectal disease2023

Short- and mid-term outcomes of abdominoperineal resection with perineal mesh insertion: a single-centre experience.

Ahmed Gendia, Masood Rehman, Cindy W Lin, Kamran Malik, Khalil Khalil, Ugo Ihedioha, Peter Kang, John Evans, Jamil Ahmed

Abstract read
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In one paragraph

Article in International journal of colorectal disease, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.5field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 2 countries.

Ahmed GendiaColorectal Department, Northampton University Hospital, Northampton, NN1 5BD, UK. ahmed.gendia@nhs.net.
Masood RehmanColorectal Department, Northampton University Hospital, Northampton, NN1 5BD, UK.
Cindy W LinColorectal Department, Northampton University Hospital, Northampton, NN1 5BD, UK.
Kamran MalikColorectal Department, Northampton University Hospital, Northampton, NN1 5BD, UK.
Khalil KhalilColorectal Department, Northampton University Hospital, Northampton, NN1 5BD, UK.
Ugo IhediohaColorectal Department, Northampton University Hospital, Northampton, NN1 5BD, UK.
Peter KangColorectal Department, Northampton University Hospital, Northampton, NN1 5BD, UK.
John EvansColorectal Department, Northampton University Hospital, Northampton, NN1 5BD, UK.
Jamil AhmedColorectal Department, Northampton University Hospital, Northampton, NN1 5BD, UK.
University of Northampton · GBNorthampton Community College · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeAbdominoperineal resection (APR) remains a key procedure for the treatment of low rectal/anorectal cancers. However, perineal wound closure remains challenging, particularly in extralevator abdominoperineal resection (ELAPR) due to gapped tissue planes. Different approaches have been attempted to improve perineal wound repair. The aim of this study is to report our 6-year experience in perineal wound closure utilising biological mesh.

methodsWe conducted a retrospective study using data from our prospectively maintained database, including patients who underwent APR with perineal mesh closure between 2016 and 2021.

results49  patients underwent APR with perineal mesh reconstruction for low rectal cancer during the 6-year period. Of these, 63% were males, with a mean age of 68 (± 11), and a mean BMI of 27.9 (± 13.7). 49% (24) of patients received neoadjuvant therapy. 88% (43) of patients underwent standard "S-APR" and only 12% (6) underwent ELAPR. Majority of procedures were laparoscopic (87.8%) with conversion rate of 6.9%. Mean length of stay was 11.7 (± 11.6). The perineal wound infection rate was 30% and only two patient required mesh removal due to entero-cutaneous perineal fistula and pelvic abscess. Perineal hernia was found in only two patients (4.1%). CRM was negative in 81.6% of the patients. Mean follow-up period was 29.2 (± 16.5) months, and disease recurrence occurred in 9 (18.3%) patients with average number of months for recurrence of 21 (± 7). Overall survival during the follow-up period was 91%.

conclusionOur series shows a favourable short- and medium-term outcome with routine insertion of mesh for perineal wound closure.

Indexed as

Cutaneous FistulaProctectomyAgedFemaleHumansMaleNeoadjuvant TherapyNeoplasm Recurrence, LocalRetrospective StudiesSurgical MeshAPRColorectal surgeryELAPRMesh reconstructionPerineal herniaQuality of life

Identifiers

PMID37606697
OpenAlexW4386046507

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.