GuidelineJAMA2023
Preexposure Prophylaxis to Prevent Acquisition of HIV: US Preventive Services Task Force Recommendation Statement.
Guideline in JAMA, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it, 57 citations in OpenAlex.
- Evaluating the effectiveness of digital health interventions for HIV prevention and treatment adherence among transgender populations: a systematic review and meta-analysis.Frontiers in microbiology · 2025Pooled it
- Safety, Tolerability, and Pharmacokinetics of Once-Monthly Oral Islatravir: A Phase 2a Study in Participants at Low Risk for Acquiring Human Immunodeficiency Virus Type 1.The Journal of infectious diseases · 2025Trial
- The Effects of MyChoices and LYNX Mobile Apps on HIV Testing and Pre-Exposure Prophylaxis Use by Young US Sexual Minority Men: Results From a National Randomized Controlled Trial.JMIR public health and surveillance · 2025Trial
- HIV Pre-Exposure Prophylaxis Care Continuum in Outpatient Settings: A Systematic Review and Meta-Analysis.AJPM focus · 2026Review
- When Training Pipelines Break: What NIH F31 Terminations Mean for the Future of Public Health Research.Health education & behavior : the official publication of the Society for Public Health Education · 2026Article
- Sexual Orientation and Gender Identity Data and HIV Preexposure Prophylaxis Disparity Detection.JAMA network open · 2026Article
- Burden of mental health symptoms and access to needed mental health care among people with HIV in New England.AIDS care · 2026Article
- PrEP at the site of action in cisgender and transgender women: A pharmacology study of blood and rectal CD4British journal of clinical pharmacology · 2026Article
- Willingness-to-Pay for HIV Pre-Exposure Prophylaxis Among Men Who Have Sex with Men in the United States.AIDS and behavior · 2026Article
- Psychosocial correlates of awareness of HIV pre-exposure prophylaxis (PrEP) among persons who inject drugs in Northeast Georgia.AIDS care · 2026Article
- A Comparative Analysis of Pre-Exposure Prophylaxis Awareness, Acceptance, and Barriers Among Populations of Men Who Have Sex with Men in Global Settings: An Integrative Literature Review.Nursing reports (Pavia, Italy) · 2026Review
- Sexually Transmitted Infection (STI)/HIV Testing, STIs, and HIV Pre-exposure Prophylaxis Use Among Men Who Have Sex With Men and Men Who Have Sex With Men and Women in the United States, 2019-2022.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026Article
- Cost-effectiveness of leveraging long-acting injectable cabotegravir to expand PrEP coverage among MSM in two contrasting North American cities.Journal of the International AIDS Society · 2026Article
- Changes in the PrEP Care Cascade in People Who Inject Drugs in 2018 and 2022.AIDS and behavior · 2025Article
- Quantifying the number of people who would benefit from HIV pre-exposure prophylaxis (PrEP) in the United States: a comparison of behavioral, acquisition-risk based, and economic metrics.medRxiv : the preprint server for health sciences · 2025Article
- Predictors and Outcomes of Right Ventricular Dysfunction in Patients Admitted to the Medical Intensive Care Unit for Sepsis-A Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- Staff and Providers' Perceptions of Patients' PrEP Candidacy, Acceptability, and Adherence in Methadone Clinic Settings.Substance use & addiction journal · 2025Article
- PrEP Navigator Perceptions of the Implementation of Injectable PrEP on HIV Prevention in Tennessee.International journal of environmental research and public health · 2025Article
- "When Somebody Comes into This Country and You Are Trans on Top of That Is Like You Got… Two Strikes on You": Intersectional Barriers to PrEP Use Among Latina Transgender Women in the Eastern and Southern United States.International journal of environmental research and public health · 2025Article
- Review
Corrections and comments
- Commented on by
- Commented on by
- Erratum issuedIncorrect Data.2023
- SummaryForPatientsIn
Authors and funding
18 authors at 11 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Importance: An estimated 1.2 million persons in the US currently have HIV, and more than 760 000 persons have died of complications related to HIV since the first cases were reported in 1981. Although treatable, HIV is not curable and has significant health consequences. Therefore, effective strategies to prevent HIV are an important public health and clinical priority. Objective: The US Preventive Services Task Force (USPSTF) commissioned a systematic review to evaluate the benefits and harms of preexposure prophylaxis with antiretroviral therapy for the prevention of HIV acquisition, and the diagnostic accuracy of risk assessment tools to identify persons at increased risk of HIV acquisition. Population: Adolescents and adults who do not have HIV and are at increased risk of HIV. Evidence Assessment: The USPSTF concludes with high certainty that there is a substantial net benefit from the use of effective antiretroviral therapy to reduce the risk of acquisition of HIV in persons at increased risk of acquiring HIV. Recommendation: The USPSTF recommends that clinicians prescribe preexposure prophylaxis using effective antiretroviral therapy to persons at increased risk of HIV acquisition to decrease the risk of acquiring HIV. (A recommendation).
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.