Evidence map›Paper›PMID 37606512›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2024

Pregnancy and Birth Outcomes in Patients With Multidrug-Resistant Tuberculosis Treated With Regimens That Include New and Repurposed Drugs.

Ismat Lotia Farrukh, Nathalie Lachenal, Malik M Adenov, Saman Ahmed, Yerkebulan Algozhin, Sylvine Coutisson, Epifanio Sánchez Garavito, Catherine Hewison, David Holtzman, Helena Huerga and 18 more

Open access · hybridAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 16 citations in OpenAlex.

  1. Trial
  2. Article
  3. Pregnant Women With Multidrug-Resistant/Rifampicin-Resistant Tuberculosis and the All-Oral 6-Month Regimen: Experiences From a Patient Series in South Africa.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2026
    Observational
  4. Observational
  5. Review
  6. Article
  7. Observational
  8. Article
  9. Review
  10. Review
  11. Review
  12. Review
  13. Adverse pregnancy outcomes and complications of tuberculosis in pregnant women.Frontiers in cellular and infection microbiology · 2025
    Review
  14. Pregnancy Outcomes in Multidrug-Resistant Tuberculosis in TB-PRACTECAL.Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · 2024
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

28 authors at 10 institutions in 6 countries.

Ismat Lotia FarrukhInteractive Research and Development Pakistan, Karachi, Pakistan.ORCID 0000-0002-5822-8505
Nathalie LachenalPharmacovigilance Unit, Médecins Sans Frontières, Geneva, Switzerland.
Malik M AdenovNational Scientific Center of Phthisiopulmonology, Ministry of Health, Republic of Kazakhstan, Almaty, Kazakhstan.
Saman AhmedInteractive Research and Development Pakistan, Karachi, Pakistan.
Yerkebulan AlgozhinPartners In Health, Almaty, Kazakhstan.
Sylvine CoutissonPharmacovigilance Unit, Médecins Sans Frontières, Geneva, Switzerland.
Epifanio Sánchez GaravitoCentro de Investigación de Enfermedades Neumológicas, Hospital Nacional Sergio Bernale, Lima, Peru.
Catherine HewisonMedical Department, Médecins Sans Frontières, Paris, France.ORCID 0000-0002-0363-1479
David HoltzmanPartners In Health, Maseru, Lesotho.
Helena HuergaField Epidemiology Department, Epicentre, Paris, France.ORCID 0000-0003-0302-9063
Aleeza JanmohamedInteractive Research and Development Pakistan, Karachi, Pakistan.
Palwasha Y KhanInteractive Research and Development Pakistan, Karachi, Pakistan.
Gamarly Leblanc JacquesZanmi Lasante, Cange, Haiti.
Nino LomtadzeSurveillance and Strategic Planning, Ministry of Health, Tbilisi, Georgia.
Nara MelikyanField Epidemiology Department, Epicentre, Yerevan, Armenia.
Carole D MitnickDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Gulnaz MussabekovaNational Scientific Center of Phthisiopulmonology, Ministry of Health, Republic of Kazakhstan, Almaty, Kazakhstan.
Elna OssoDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Sara PereaSocios En Salud Sucursal Peru, Lima, Peru.
Fauziah Asnely PutriInteractive Research and Development Global, Jakarta, Indonesia.
Mahmud RashidovPartners In Health, Almaty, Kazakhstan.
Michael L RichPartners In Health, Boston, Massachusetts, USA.
Yekaterina SakhabutdinovaPartners In Health, Almaty, Kazakhstan.
Kwonjune J SeungPartners In Health, Boston, Massachusetts, USA.
Assel StambekovaPartners In Health, Almaty, Kazakhstan.
Dante Vargas VásquezCentro de Investigación, Hospital Nacional Hipólito Unanue, Lima, Peru.
Molly F FrankeDepartment of Global Health and Social Medicine, Harvard Medical School, Boston, Massachusetts, USA.
Uzma KhanInteractive Research and Development Pakistan, Karachi, Pakistan.
Interactive Research and Development · PKBrigham and Women's Hospital · USHarvard University · USMédecins Sans Frontières · CHPartners In Health · USEsSALUD · PEHospital Nacional Cayetano Heredia · PELondon School of Hygiene & Tropical Medicine · GBMédecins Sans Frontières · FRUniversidad Privada Sergio Bernales · PE

Funding

Strengthening evidence on optimal multidrug-resistant tuberculosis treatment regimens through improved epidemiologic methodsR01AI146095 · NIAID · HARVARD MEDICAL SCHOOL · PI FRANKE, MOLLY FORREST · 2020 to 2024
$3.6M
NIAID NIH HHS R01 AI146095
6 · The paper itself

Abstract

Among 43 pregnant women receiving multidrug-resistant/rifampicin-resistant tuberculosis (MDR/RR-TB) treatment with bedaquiline and/or delamanid, 98% had favorable treatment outcomes. Of 31 continued pregnancies, 81% had live births with no reported malformations, and 68% of neonates had normal birth weights. Effective MDR/RR-TB treatment during pregnancy can improve maternal outcomes without harming neonates.

Indexed as

Antitubercular AgentsTuberculosis, Multidrug-ResistantClinical ProtocolsDiarylquinolinesFemaleHumansInfant, NewbornLive BirthPregnancyTreatment OutcomeAntitubercular AgentsDiarylquinolinesdrug resistanceoutcomepregnancytreatmenttuberculosis

Identifiers

PMID37606512
PMCPMC10810705
OpenAlexW4386045833

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.