Evidence map›Paper›PMID 37606478›Full record

ArticleInternational journal of neonatal screening2023

Comparison between Gibson-Cooke and Macroduct Methods in the Cystic Fibrosis Neonatal Screening Program and in Subjects Who Are Cystic Fibrosis Screen-Positive with an Inconclusive Diagnosis.

Daniela Dolce, Cristina Fevola, Erica Camera, Tommaso Orioli, Ersilia Lucenteforte, Marco Andrea Malanima, Giovanni Taccetti, Vito Terlizzi

Open access · goldAbstract read
In one paragraph

Article in International journal of neonatal screening, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
2.1field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Daniela DolceCystic Fibrosis Regional Reference Center, Department of Paediatric Medicine, Meyer Children's Hospital IRCCS, Viale Gaetano Pieraccini 24, 50139 Florence, Italy.ORCID 0000-0002-8317-9928
Cristina FevolaCystic Fibrosis Regional Reference Center, Department of Paediatric Medicine, Meyer Children's Hospital IRCCS, Viale Gaetano Pieraccini 24, 50139 Florence, Italy.ORCID 0000-0002-3642-8928
Erica CameraCystic Fibrosis Regional Reference Center, Department of Paediatric Medicine, Meyer Children's Hospital IRCCS, Viale Gaetano Pieraccini 24, 50139 Florence, Italy.
Tommaso OrioliCystic Fibrosis Regional Reference Center, Department of Paediatric Medicine, Meyer Children's Hospital IRCCS, Viale Gaetano Pieraccini 24, 50139 Florence, Italy.ORCID 0000-0003-3724-7501
Ersilia LucenteforteUnit of Medical Statistics, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.ORCID 0000-0001-5608-5902
Marco Andrea MalanimaUnit of Medical Statistics, Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Giovanni TaccettiCystic Fibrosis Regional Reference Center, Department of Paediatric Medicine, Meyer Children's Hospital IRCCS, Viale Gaetano Pieraccini 24, 50139 Florence, Italy.ORCID 0000-0002-9448-5381
Vito TerlizziCystic Fibrosis Regional Reference Center, Department of Paediatric Medicine, Meyer Children's Hospital IRCCS, Viale Gaetano Pieraccini 24, 50139 Florence, Italy.ORCID 0000-0003-1106-4424
Meyer Children's Hospital · ITUniversity of Pisa · IT

Funding

Fondazione per la Ricerca sulla Fibrosi Cistica FFC#30/2018; FFC#24/2020
6 · The paper itself

Abstract

The sweat test (ST) is the current diagnostic gold standard for cystic fibrosis (CF). Many CF centres have switched from the Gibson-Cooke method to the Macroduct system-based method. We used these methods simultaneously to compare CF screening outcomes. STs using both methods were performed simultaneously between March and December 2022 at CF Centre in Florence. We included newborns who underwent newborn bloodspot screening (NBS), newborns undergoing transfusion immediately after birth, and children with CF screen-positive, inconclusive diagnosis (CFSPID). We assessed 72 subjects (median age 4.4 months; range 0-76.7): 30 (41.7%) NBS-positive, 18 (25.0%) newborns who underwent transfusion, and 24 (33.3%) children with CFSPID. No significant differences were found between valid sample numbers, by patient ages and groups (

Indexed as

CRMS/CFSPIDcystic fibrosis outcomeGibson–Cooke methodmacroduct system-based methodQNSsweat test

Identifiers

PMID37606478
PMCPMC10443242
OpenAlexW4385272844

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.