Evidence map›Paper›PMID 37606472›Full record

ArticleDiseases (Basel, Switzerland)2023

The Association of Cytomegalovirus and Allostatic Load by Country of Birth and Length of Time in the United States.

Matthew Hill, Sayed Mostafa, Perpetua M Muganda, Liesl K Jeffers-Francis, Emmanuel Obeng-Gyasi

Open access · goldAbstract read
In one paragraph

Article in Diseases (Basel, Switzerland), 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 5 citations in OpenAlex.

  1. Article
  2. Article
  3. Chronic Stress Indicator: A Novel Tool for Comprehensive Stress Analysis.International journal of environmental research and public health · 2024
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Matthew HillDepartment of Built Environment, North Carolina A&T State University, Greensboro, NC 27411, USA.
Sayed MostafaDepartment of Mathematics and Statistics, North Carolina A&T State University, Greensboro, NC 27411, USA.ORCID 0000-0002-8113-702X
Perpetua M MugandaDepartment of Biology, North Carolina A&T State University, Greensboro, NC 27411, USA.ORCID 0000-0001-5928-6822
Liesl K Jeffers-FrancisDepartment of Biology, North Carolina A&T State University, Greensboro, NC 27411, USA.ORCID 0000-0001-7725-6336
Emmanuel Obeng-GyasiDepartment of Built Environment, North Carolina A&T State University, Greensboro, NC 27411, USA.ORCID 0000-0003-3195-706X
North Carolina Agricultural and Technical State University · US

Funding

PRIDE SUMMER INSTITUTE IN CARDIOVASCULAR GENETIC EPIDEMIOLOGYR25HL105400 · NHLBI · WASHINGTON UNIVERSITY · PI DAVILA-ROMAN, VICTOR G., DE LAS FUENTES, LISA · 2010 to 2025
$5.2M
Foundation for the National Institutes of Health NHLBI grant R25 HL105400NHLBI NIH HHS R25 HL105400
6 · The paper itself

Abstract

backgroundCytomegalovirus (CMV) is a highly prevalent virus with a worldwide distribution. It typically remains dormant in most individuals until reactivation. Immunocompromised states are known to be potential causes for CMV reactivation. Current research has shown a link in the decline of immigrant health among those living in the US for an extended period, though the impact of CMV on this is not clear.

methodsThis study investigated the association between country of birth, duration of US residency, allostatic load, and latent cytomegalovirus infection (CMV IgG) in a sample of US adults aged 20-49. The data utilized for our analysis was obtained from the National Health and Nutrition Examination Survey (NHANES) conducted between 2001 and 2004. Allostatic load, an index measuring the cumulative physiological strain on the body as it strives to regain stability in the presence of chronic stress, provided a valuable approach to assess stress within the context of CMV exposure. Logistic regression modeling was employed to estimate odds ratios and confidence intervals for the analysis. The chi-square test of association and Cramer's V statistic were used to assess the correlation among categorical variables, while Pearson's correlation coefficient was applied to evaluate the relationship between continuous variables. The results revealed that individuals born outside the US and those with less than 20 years of residency in the US exhibited significantly higher proportions of positive CMV IgG compared to individuals born in the US. Specifically, individuals born outside the US had more than triple the odds of CMV IgG when adjusting for the AL index (OR = 3.69,

Indexed as

allostatic loadcountry of birthcytomegaloviruslength of time in USstress

Identifiers

PMID37606472
PMCPMC10443278
OpenAlexW4385576089

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.