Evidence map›Paper›PMID 37606453›Full record

ReviewEpigenomes2023

Evaluation of Exosomal miRNA as Potential Biomarkers in Cervical Cancer.

Jéssika Aline do Nascimento Medeiros, Ayane Cristine Alves Sarmento, Emanuelly Bernardes-Oliveira, Ronnier de Oliveira, Maysa Eunice Grigorio Bezerra Lima, Ana Katherine Gonçalves, Deyse de Souza Dantas, Janaina Cristiana de Oliveira Crispim

Open access · diamondAbstract readReview
In one paragraph

Review in Epigenomes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Exosomal ncRNAs in reproductive cancers†.Biology of reproduction · 2025
    Review
  5. Review
  6. Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Jéssika Aline do Nascimento MedeirosWomen's Health Sciences Postgraduate Program, Federal University of Rio Grande do Norte (UFRN), Natal 59012-570, RN, Brazil.
Ayane Cristine Alves SarmentoHealth Sciences Postgraduate Program, Federal University of Rio Grande do Norte (UFRN), Natal 59012-570, RN, Brazil.ORCID 0000-0001-9131-1952
Emanuelly Bernardes-OliveiraSpecialization Program in Oncotic Gynecological Cytology, Januário Cicco Maternity School, Natal 59012-300, RN, Brazil.ORCID 0000-0003-4673-9209
Ronnier de OliveiraUndergraduate Course in Medicine, Federal University of Rio Grande do Norte (UFRN), Natal 59012-570, RN, Brazil.ORCID 0000-0002-8233-5116
Maysa Eunice Grigorio Bezerra LimaUndergraduate Course in Biomedicine, Federal University of Rio Grande do Norte (UFRN), Natal 59012-570, RN, Brazil.
Ana Katherine GonçalvesWomen's Health Sciences Postgraduate Program, Federal University of Rio Grande do Norte (UFRN), Natal 59012-570, RN, Brazil.ORCID 0000-0002-8351-5119
Deyse de Souza DantasSpecialization Program in Oncotic Gynecological Cytology, Januário Cicco Maternity School, Natal 59012-300, RN, Brazil.ORCID 0000-0002-8284-0999
Janaina Cristiana de Oliveira CrispimWomen's Health Sciences Postgraduate Program, Federal University of Rio Grande do Norte (UFRN), Natal 59012-570, RN, Brazil.ORCID 0000-0002-1344-0078
Universidade Federal do Rio Grande do Norte · BR

Funding

Coordination for the Improvement of Higher Education Personnel - Brazil (CAPES) Financial Code 001
6 · The paper itself

Abstract

Different studies show that small non-coding RNAs, such as microRNAs (miRNAs) obtained from exosomes, are considered potential biomarkers in several types of cancer, including cervical cancer (CC). Therefore, the present study seeks to present an overview of the role of circulating exosomal miRNAs with the potential to act as biomarkers for the diagnosis and prognosis of CC and to analyze the presence of these miRNAs according to the stage of CC. For this purpose, a review was developed, with articles consulted from the electronic databases MEDLINE/PubMed, Scopus, and Web of Science published between 2015 and 2021. Seven articles were included after a selection of studies according to the eligibility criteria. In addition to the methods used for sample analysis, detection, and isolation of miRNAs in each article, clinical data were also extracted from the patients studied, such as the stage of cancer. After analyzing the network of the seven miRNAs, they were associated with the immune system, CC progression and staging, and cisplatin resistance. With the belief that studies on miRNAs in cervical cancer would have major clinical implications, in this review, we have attempted to summarize the current situation and potential development prospects.

Indexed as

biomarkerscervical cancerexosomesmiRNAs

Identifiers

PMID37606453
PMCPMC10443249
OpenAlexW4385462776

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.