Evidence map›Paper›PMID 37606452›Full record

ArticleEpigenomes2023

Association of Toll-Like Receptor Gene Polymorphisms with Tuberculosis in HIV-Positive Participants.

Svetlana Salamaikina, Vitaly Korchagin, Ekaterina Kulabukhova, Konstantin Mironov, Vera Zimina, Alexey Kravtchenko, Vasily Akimkin

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Epigenomes, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.8field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Svetlana SalamaikinaCentral Research Institute of Epidemiology Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing Russian Federation, Novogireevskaya Str. 3a, 111123 Moscow, Russia.ORCID 0000-0002-2517-5048
Vitaly KorchaginCentral Research Institute of Epidemiology Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing Russian Federation, Novogireevskaya Str. 3a, 111123 Moscow, Russia.ORCID 0000-0003-2264-6294
Ekaterina KulabukhovaCentral Research Institute of Epidemiology Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing Russian Federation, Novogireevskaya Str. 3a, 111123 Moscow, Russia.
Konstantin MironovCentral Research Institute of Epidemiology Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing Russian Federation, Novogireevskaya Str. 3a, 111123 Moscow, Russia.ORCID 0000-0001-8207-9215
Vera ZiminaMedical Institute, The Peoples' Friendship University of Russia (RUDN University), Miklukho-Maklaya Str. 6, 117198 Moscow, Russia.
Alexey KravtchenkoCentral Research Institute of Epidemiology Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing Russian Federation, Novogireevskaya Str. 3a, 111123 Moscow, Russia.
Vasily AkimkinCentral Research Institute of Epidemiology Federal Service for Surveillance on Consumer Rights Protection and Human Wellbeing Russian Federation, Novogireevskaya Str. 3a, 111123 Moscow, Russia.
Central Research Institute of Epidemiology · RUPeoples' Friendship University of Russia · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic factors in the HIV-background may play a significant role in the susceptibility to secondary diseases, like tuberculosis, which is the leading cause in mortality of HIV-positive people. Toll-like receptors (TLRs) are considered to be receptors for adaptive immunity, and polymorphisms in TLR genes can influence the activity of the immune response to infection. We conducted a case-control study of the association of TLR gene polymorphisms with the risk of tuberculosis coinfection in a multi-country sample of HIV-positive participants. Our study revealed certain associations between

Indexed as

CD4 cellsgenetic susceptibilityHIVinfectious diseaseSNPTLRtuberculosis

Identifiers

PMID37606452
PMCPMC10443360
OpenAlexW4385277484

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.