Evidence map›Paper›PMID 37606091›Full record

ArticlePublic health nutrition2023

The cost-effectiveness of small-quantity lipid-based nutrient supplements for prevention of child death and malnutrition and promotion of healthy development: modelling results for Uganda.

Katherine P Adams, Stephen A Vosti, Charles D Arnold, Reina Engle-Stone, Elizabeth L Prado, Christine P Stewart, K Ryan Wessells, Kathryn G Dewey

Abstract read
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Article in Public health nutrition, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Katherine P AdamsInstitute for Global Nutrition, University of California, Davis, CA95616, USA.ORCID 0000-0002-1060-2473
Stephen A VostiDepartment of Agricultural and Resource Economics, University of California, Davis, CA, USA.
Charles D ArnoldInstitute for Global Nutrition, University of California, Davis, CA95616, USA.
Reina Engle-StoneInstitute for Global Nutrition, University of California, Davis, CA95616, USA.
Elizabeth L PradoInstitute for Global Nutrition, University of California, Davis, CA95616, USA.
Christine P StewartInstitute for Global Nutrition, University of California, Davis, CA95616, USA.ORCID 0000-0003-4575-8571
K Ryan WessellsInstitute for Global Nutrition, University of California, Davis, CA95616, USA.
Kathryn G DeweyInstitute for Global Nutrition, University of California, Davis, CA95616, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveRecent meta-analyses demonstrate that small-quantity lipid-based nutrient supplements (SQ-LNS) for young children significantly reduce child mortality, stunting, wasting, anaemia and adverse developmental outcomes. Cost considerations should inform policy decisions. We developed a modelling framework to estimate the cost and cost-effectiveness of SQ-LNS and applied the framework in the context of rural Uganda.

designWe adapted costs from a costing study of micronutrient powder (MNP) in Uganda, and based effectiveness estimates on recent meta-analyses and Uganda-specific estimates of baseline mortality and the prevalence of stunting, wasting, anaemia and developmental disability.

settingRural Uganda.

participantsNot applicable.

resultsProviding SQ-LNS daily to all children in rural Uganda (> 1 million) for 12 months (from 6 to 18 months of age) via the existing Village Health Team system would cost ∼$52 per child (2020 US dollars) or ∼$58·7 million annually. SQ-LNS could avert an average of > 242 000 disability-adjusted life years (DALYs) annually as a result of preventing 3689 deaths, > 160 000 cases of moderate or severe anaemia and ∼6000 cases of developmental disability. The estimated cost per DALY averted is $242.

conclusionsIn this context, SQ-LNS may be more cost-effective than other options such as MNP or the provision of complementary food, although the total cost for a programme including all age-eligible children would be high. Strategies to reduce costs, such as targeting to the most vulnerable populations and the elimination of taxes on SQ-LNS, may enhance financial feasibility.

Indexed as

AnemiaMalnutritionTrace ElementsChildChild, PreschoolCost-Benefit AnalysisDietary SupplementsGrowth DisordersHumansInfantLipidsMicronutrientsUgandaLipidsMicronutrientsTrace ElementsCost-effectivenessDisability-adjusted life yearsEconomic analysisNutrient supplementsUganda

Identifiers

PMID37606091
PMCPMC10564609

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.