Evidence map›Paper›PMID 37606007›Full record

ArticleTurkish journal of pharmaceutical sciences2023

LC-MS/MS Method Development and Validation for Determination of Favipiravir Pure and Tablet Dosage Forms.

Nandeesha Itigimath, Hadagali Ashoka, Basappa C Yallur, Manjunatha Devagondanahalli Hadagali

Abstract read
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Article in Turkish journal of pharmaceutical sciences, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Nandeesha ItigimathRamaiah Institute of Technology, Department of Chemistry, Visvesvaraya Technological University, Bangalore, Belagavi, India.ORCID 0000-0002-7220-6003
Hadagali AshokaBMS College of Engineering, Department of Biotechnology, Bengalore, India.ORCID 0000-0002-5312-6032
Basappa C YallurRamaiah Institute of Technology, Department of Chemistry, Visvesvaraya Technological University, Bangalore, Belagavi, India.ORCID 0000-0002-9099-7056
Manjunatha Devagondanahalli HadagaliDavangere University, Department of Studies in Chemistry, Davangere, India.ORCID 0000-0002-0634-6198

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: Analytical method development and validation for determination of favipiravir (FVPR) in pure and tablet dosage forms by liquid chromatography with tandem mass spectrometry/mass spectrometry (LC-MS/MS) technique. Materials and Methods: A simple LC-MS/MS method was developed for determination of a new antiviral drug, FVPR in pharmaceutical formulations. The stationary phase employed was a Shim pack GISS, C Results: The linearity graph was found in the range of 50-200 μg/mL and the correlation coefficient value (R Conclusion: All outcomes obtained comply with ICH guidelines. The developed method was simple, unique, accurate, robust, precise, and reproducible for determination of FVPR in tablet formulation. The method is novel and could be adopted in formulation industry.

Indexed as

FavipiravirLC-MS/MSmethod developmentmethod validationquantification

Identifiers

PMID37606007
PMCPMC10445228

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.