Evidence map›Paper›PMID 37605863›Full record

ArticleJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine2023

Correlation of Ocular Plane-Wave Doppler With Optical Coherence Tomography Angiography in Preeclampsia.

Ronald H Silverman, Raksha Urs, Ronald J Wapner, Ives A Valenzuela, Hanna R Coleman, Srilaxmi Bearelly

Open access · bronzeAbstract read
In one paragraph

Article in Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ronald H SilvermanDepartment of Ophthalmology, Columbia University Irving Medical Center, New York, NY, USA.ORCID https://orcid.org/0000-0003-1509-3011
Raksha UrsDepartment of Ophthalmology, Columbia University Irving Medical Center, New York, NY, USA.
Ronald J WapnerDepartment of Obstetrics and Gynecology, Columbia University Irving Medical Center, New York, NY, USA.
Ives A ValenzuelaDepartment of Ophthalmology, Columbia University Irving Medical Center, New York, NY, USA.
Hanna R ColemanDepartment of Ophthalmology, Columbia University Irving Medical Center, New York, NY, USA.
Srilaxmi BearellyDepartment of Ophthalmology, Columbia University Irving Medical Center, New York, NY, USA.
Columbia University Irving Medical Center · US

Funding

Clinical and Translational Science AwardUL1TR001873 · NCATS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI REILLY, MUREDACH P · 2016 to 2025
$99.0M
Instrumentation, Fabrication, and Design CoreP30EY019007 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI Xin Zhang · 2010 to 2026
$12.9M
Ultrasound perfusion imaging in glaucomaR01EY025215 · NEI · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI SILVERMAN, RONALD H · 2015 to 2018
$1.9M
NCATS NIH HHS UL1 TR001873NCATS NIH HHS UL1TR001873NEI NIH HHS P30 EY019007NEI NIH HHS R01 EY025215NIH HHS P30 EY019007NIH HHS R01 EY025215
6 · The paper itself

Abstract

objectivesPreeclampsia (PE) is a severe complication of pregnancy characterized by hypertension, proteinuria and compromised fetal blood supply. The eye, like other end organs, is affected by this systemic condition, but unlike in other organs, ocular media transparency allows high-resolution optical visualization of the vascular structure of the retina. Our aim was to assess how ultrasound-determined ocular blood-flow correlates with vascular structure of the retina and choriocapillaris determined by optical coherence tomography angiography (OCTA).

methodsPlane-wave ultrasound and OCTA were performed on both eyes of 40 consecutive subjects consisting of normal controls (n = 11), mild PE (n = 5), severe PE (n = 17) and chronic or gestational hypertension (n = 7) within 72 hours following delivery. From ultrasound, we measured pulsatile flow velocity and resistance indices in the central retinal artery (CRA) and vein, the short posterior ciliary arteries (SPCAs) and choroid. From OCTA, we measured vascular density (VD) in the superficial, deep retina and choriocapillaris. We determined differences in Doppler and OCTA parameters among groups and correlations between ultrasound and OCTA.

resultsIn severe PE, flow resistance was reduced with respect to controls. Flow velocity and resistance in the and SPCA were moderately correlated with VD in the choriocapillaris and peripapillary retina, but VD in PE did not differ significantly from controls.

conclusionsAlthough OCTA parameters were moderately correlated with Doppler ultrasound, OCTA did not demonstrate significant differences between PE and controls postpartum.

Indexed as

Pre-EclampsiaRetinal VesselsFemaleFluorescein AngiographyHumansPregnancyTomography, Optical CoherenceUltrasonography, Dopplerblood floweyeoptical coherence tomography angiographyplane-wave Dopplerpreeclampsiaultrasound

Identifiers

PMID37605863
PMCPMC10840834
OpenAlexW4386045776

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.