Evidence map›Paper›PMID 37605538›Full record

ArticleClinical and experimental pediatrics2024

Influence of infant microbiome on health and development.

Noelle Younge

Abstract read
In one paragraph

Article in Clinical and experimental pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Impact ofFrontiers in nutrition · 2026
    Trial
  2. Article
  3. Observational
  4. Review
  5. Article
  6. The importance of gut microbiome in the perinatal period.European journal of pediatrics · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Noelle YoungeDuke University School of Medicine, Durham, NC, USA.

Funding

The Microbiome and Metabolism in Postnatal Growth FailureK23DK120960 · NIDDK · DUKE UNIVERSITY · PI YOUNGE, NOELLE ELIZABETH · 2019 to 2022
$874k
Bacterial mediators of postnatal growth in preterm infantsR03DK134684 · NIDDK · DUKE UNIVERSITY · PI YOUNGE, NOELLE ELIZABETH · 2023 to 2024
$237k
NIDDK NIH HHS K23 DK120960NIDDK NIH HHS R03 DK134684NIH HHS K23DK120960NIH HHS R03DK134684
6 · The paper itself

Abstract

The microbiome is a complex ecosystem comprising microbes, their genomes, and the surrounding environment. The microbiome plays a critical role in early human development, including maturation of the host immune system and gastrointestinal tract. Multiple factors, including diet, anti-biotic use, and other environmental exposures, influence the establishment of the microbiome during infancy. Numerous studies have identified associations between the microbiome and neonatal diseases, including necrotizing enterocolitis, sepsis, and malnutrition. Furthermore, there is compelling evidence that perturbation of the microbiome in early life can have lasting developmental effects that increase an individual's risk for immune and metabolic diseases in later life. Supplementation of the microbiome with probiotics reduces the risk of necrotizing enterocolitis and sepsis in at-risk infants. This review focuses on the structure and function of the infant microbiome, the environmental and clinical factors that influence its assembly, and its impact on infant health and development.

Indexed as

Host-microbiome interactionMicrobiomeNeonate infant

Identifiers

PMID37605538
PMCPMC11065641

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.