ArticleNeuropsychopharmacology reports2023
Differences in self-reported psychotic symptoms between patients with autism spectrum disorder and those with schizophrenia.
Article in Neuropsychopharmacology reports, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Loneliness despite social integration: subjective loneliness without social isolation as a risk factor for psychotic-like experiences.Annals of general psychiatry · 2026Article
- Differential Associations of Adversity and Victimisation With Psychotic Experiences in Autistic Adolescents.Journal of autism and developmental disorders · 2026Article
- Initial psychotropic prescriptions and symptom associations in first-visit patients with major depressive disorder: A single-center cross-sectional study.Neuropsychopharmacology reports · 2025Article
- Predictors of Changes in Depressive Symptoms with Major Depressive Disorder - A Naturalistic 6-month Follow-up Study.Neuropsychiatric disease and treatment · 2025Article
- Features of mismatch negativity in an at-risk mental state with the traits associated with the autistic spectrum.Frontiers in psychiatry · 2025Article
- Changes in suicidal ideation during treatment among patients with major depressive disorder: A 6-month naturalistic follow-up study.Neuropsychopharmacology reports · 2024Article
- Differences in self-reported psychotic symptoms between patients with autism spectrum disorder and those with schizophrenia.Neuropsychopharmacology reports · 2023Article
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4 authors.
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Abstract
aimPatients with autism spectrum disorder (ASD) are prone to develop overt psychosis and share symptom presentations with those with schizophrenia (SZ). This study aimed to explore differences in the distributions of psychotic symptoms among first-visit patients with ASD, SZ, or a nonpsychiatric diagnosis (N-PD).
methodsData from first-visit patients were retrospectively collected from medical records from the Department of Psychiatry, Dokkyo Medical University Hospital between June 2019 and May 2021. A total of 254 patients with data on the PRIME Screen-Revised (PS-R) assessments were included in our analysis. In the hospital, all psychiatric diagnoses were based on the DSM-5 diagnostic criteria.
resultsIn the ASD, SZ, and N-PD groups, endorsements of perplexity and delusional mood were 15.6% (7/45), 41.5% (44/106), and 1.1% (1/88), and those of perceptual abnormalities were 11.1% (5/45), 40.6% (43/106), and 2.3% (2/88), respectively. Trend analysis clarified that the endorsement of these psychotic symptoms increased from N-PD to ASD and SZ. In the multivariate-adjusted multinomial logistic regression analysis, the ASD and N-PD groups were compared with the SZ group. Higher age and the presence of perceptual abnormalities were associated with lack of an ASD diagnosis, whereas male sex, lack of perplexity and delusional mood, and lack of perceptual abnormalities were associated with N-PD.
conclusionOur results are preliminary; however, a detailed assessment of positive symptoms might facilitate differentiation between ASD and SZ.
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