Evidence map›Paper›PMID 37605149›Full record

ReviewCancer cell international2023

Current status of skin cancers with a focus on immunology and immunotherapy.

Mahsa Khayyati Kohnehshahri, Aila Sarkesh, Leila Mohamed Khosroshahi, Zanyar HajiEsmailPoor, Ali Aghebati-Maleki, Mehdi Yousefi, Leili Aghebati-Maleki

Open access · goldAbstract readReview
In one paragraph

Review in Cancer cell international, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 1 pooled it
11.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 1 synthesis or guideline pooled it, 71 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Mahsa Khayyati Kohnehshahri *Department of Microbiology, Faculty of Veterinary Medicine, Urmia University, Urmia, Iran.
Aila Sarkesh *Student's Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Leila Mohamed KhosroshahiDepartment of Immunology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Zanyar HajiEsmailPoorStudent's Research Committee, Tabriz University of Medical Sciences, Tabriz, Iran.
Ali Aghebati-MalekiStem Cell Research Center, Tabriz University of Medical Science, Tabriz, Iran.
Mehdi YousefiDepartment of Immunology, School of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran.
Leili Aghebati-MalekiImmunology Research Center, Tabriz University of Medical Science, Tabriz, Iran. leili_aghebati_maleki@yahoo.com.
Tabriz University of Medical Sciences · IRTehran University of Medical Sciences · IRUniversity of Tabriz · IRUrmia University · IR

Funding

Research Vice- Chancellor at Tabriz University of Medical Sciences, Iran 66813Research Vice- Chancellor at Tabriz University of Medical Sciences, Iran 66841Student Research Committee, Tabriz University of Medical Sciences 71408
6 · The paper itself

Abstract

Skin cancer is one of the most widespread cancers, with a significant global health effect. UV-induced DNA damage in skin cells triggers them to grow and proliferate out of control, resulting in cancer development. Two common types of skin cancer include melanoma skin cancer (MSC) and non-melanoma skin cancer (NMSC). Melanoma is the most lethal form of skin cancer, and NMSC includes basal cell carcinoma (BCC), squamous cell carcinoma (SCC), and other forms. The incidence of skin cancer is increasing in part owing to a demographic shift toward an aging population, which is more prone to NMSC, imposing a considerable financial strain on public health services. The introduction of immunostimulatory approaches for cancer cell eradication has led to significant improvements in skin cancer treatment. Over the last three decades, monoclonal antibodies have been used as powerful human therapeutics besides scientific tools, and along with the development of monoclonal antibody production and design procedures from chimeric to humanized and then fully human monoclonal antibodies more than 6 monoclonal antibodies have been approved by the food and drug administration (FDA) and have been successful in skin cancer treatment. In this review, we will discuss the epidemiology, immunology, and therapeutic approaches of different types of skin cancer.

Indexed as

MelanomaMonoclonal antibodyNon-melanoma skin cancerSkin cancer

Identifiers

PMID37605149
PMCPMC10440946
OpenAlexW4386030697

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.