Evidence map›Paper›PMID 37603841›Full record

Trial reportAge and ageing2023

The facilitators and barriers to improving functional activity and wellbeing in people with dementia: a qualitative study from the process evaluation of Promoting Activity, Independence and Stability in Early Dementia (PrAISED).

Claudio Di Lorito, Veronika van der Wardt, Kristian Pollock, Louise Howe, Vicky Booth, Pip Logan, John Gladman, Tahir Masud, Roshan das Nair, Sarah Goldberg and 13 more

Open access · hybridAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Age and ageing, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 7 institutions in 4 countries.

Claudio Di LoritoDivision of Primary Care and Population Health, University College London, UK.ORCID 0000-0002-8953-0117
Veronika van der WardtInstitute of General Practice, University of Marburg, Germany.
Kristian PollockSchool of Health Sciences, University of Nottingham, UK.ORCID 0000-0002-6836-8595
Louise HoweSchool of Medicine, University of Nottingham, UK.
Vicky BoothSchool of Medicine, University of Nottingham, UK.ORCID 0000-0002-5338-0196
Pip LoganSchool of Medicine, University of Nottingham, UK.
John GladmanSchool of Medicine, University of Nottingham, UK.
Tahir MasudNottingham University Hospitals NHS Trust, UK.
Roshan das NairHealth Services Research, SINTEF Digital, Norway.
Sarah GoldbergSchool of Health Sciences, University of Nottingham, UK.
Kavita VedharaSchool of Medicine, University of Nottingham, UK.
Rebecca O'BrienSchool of Medicine, University of Nottingham, UK.
Emma AdamsSchool of Medicine, University of Nottingham, UK.
Alison CowleySchool of Medicine, University of Nottingham, UK.
Alessandro BoscoPrimary Care Unit, University of Cambridge, UK.
Jennie HancoxSchool of Sport, Exercise and Health Sciences, Loughborough University, UK.
Clare BurgonSchool of Health Sciences, University of Nottingham, UK.ORCID 0000-0002-4910-9969
Rupinder BajwaSchool of Medicine, University of Nottingham, UK.
Juliette LockSchool of Medicine, University of Nottingham, UK.
Annabelle LongSchool of Medicine, University of Nottingham, UK.ORCID 0000-0003-2220-6774
Maureen GodfreySchool of Medicine, University of Nottingham, UK.
Marianne DunlopSchool of Medicine, University of Nottingham, UK.
Rowan H HarwoodSchool of Health Sciences, University of Nottingham, UK.
University of Nottingham · GBNottingham University Hospitals NHS Trust · GBLoughborough University · GBPhilipps University of Marburg · DESINTEF · NOUniversity College London · GBUniversity of Cambridge · GB

Funding

Department of Health RP-PG-0614- 20,007
6 · The paper itself

Abstract

backgroundThe PRomoting Activity, Independence and Stability in Early Dementia (PrAISED) study delivered an exercise and functional activity programme to participants living with dementia. A Randomised Controlled Trial showed no measurable benefits in activities of daily living, physical activity or quality of life.

objectiveTo explore participants' responses to PrAISED and explain why an intervention that might be expected to have produced measurable health gains did not do so.

methodsA process evaluation using qualitative methods, comprising interviews and researcher notes.

settingData were collected in participants' homes or remotely by telephone or videoconferencing. SAMPLE: A total of 88 interviews were conducted with 44 participants living with dementia (n = 32 intervention group; n = 12 control group) and 39 caregivers. A total of 69 interviews were conducted with 26 therapists.

resultsParticipants valued the intervention as proactively addressing health issues that were of concern to them, and as a source of social contact, interaction, information and advice. Facilitators to achieving positive outcomes included perceiving progress towards desired goals, positive expectations, therapists' skills and rapport with participants, and caregiver support. Barriers included: cognitive impairment, which prevented independent engagement and carry-over between sessions; chronic physical health problems and intercurrent acute illness and injury; 'tapering' (progressively infrequent supervision intended to help develop habits and independent activity); and the COVID-19 pandemic.

conclusionsSelf-directed interventions may not be appropriate in the context of dementia, even in the mild stages of the condition. Dementia-specific factors affected outcomes including caregiver support, rapport with therapists, availability of supervision, motivational factors and the limitations of remote delivery. The effects of cognitive impairment, multimorbidity and frailty overwhelmed any positive impact of the intervention. Maintenance of functional ability is valued, but in the face of inevitable progression of disease, other less tangible outcomes become important, challenging how we frame 'health gain' and trial outcomes.

Indexed as

COVID-19DementiaActivities of Daily LivingHumansPandemicsQuality of Lifedementiaexerciseolder peopleprocess evaluationqualitative research

Identifiers

PMID37603841
PMCPMC10442073
OpenAlexW4386025941

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.